Báo cáo y học: "Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD" ppsx
Báo cáo y học: "Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD" ppsx
... downregulation of decorin gene expression in COPD patients, at least partially via the Smad pathway. Our findings may explain why only a sub- set of smokers demonstrates an excess parenchymal ECM destruction ... inadequate in a subset of smokers, leading to gradually increasing parenchymal ECM destruction and emphysematous changes [9]. We addressed three ques- tions to obtain more...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Differential gene expression in HIV/SIV-associated and spontaneous lymphomas"
... gene; IL5: the interleukin 5 gene; λ Ig: the λ -chain of immunoglobulin gene; γIg: the γ-chain of immunoglobulin gene; IFN-ind: the interferon-inducible gene 6-16; IL4R: the interleukin ... dehydrogenase subunit 4 gene, IL5 – the interleukin 5 gene, λ Ig – the λ -chain of immunoglobulin gene, γIg – the γ-chain of immunoglobulin gene, IFN-ind – the interferone-inducible gene...
Ngày tải lên: 02/11/2012, 11:08
Báo cáo y học: "Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats" potx
... analyzed individually. Flow cytometry analysis The cell type composition and level of protein expression for some genes in the inguinal lymph nodes were analyzed by flow cytometry. Single cell ... QTLs, and therefore microarray analysis may be a valuable tool for cloning arthritis controlling genes and improving our understanding of their biological pathways. Therefore, microarray ana...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx
... previously reported data showing an age-related increase in OCN gene expression in OA and a decrease in controls [16]. This finding is supportive of an increase or main- tenance of bone volume in OA individuals ... matrix. Increased OPN may augment OB synthetic activity by increasing OB longevity and surface extent of bone formation. Hence, increased OPN mRNA expression in OA...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Host gene expression profiling in influenza A virus-infected lung epithelial (A549) cells: a comparative analysis between highly pathogenic and modified H5N1 viruses" ppt
... include overactive inflammatory response in the form of hypercy- tokinemia (cytokine storm), that is initiated inside the infected cells or tissue in response to virus replication resulting in ... 28 genes were found to have differential expression pattern and were mainly involved in Cytokine-cytokine receptor interaction, Toll like-receptor mediated signal- ing and p53 signaling pa...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: " Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth" pptx
... <.05) within 21 days of pneumonectomy. Cluster analysis of the 22 genes indicated that changes in gene expression did not occur in a single phase, but in at least four waves of gene expression: ... phe- notypically uniform cell type (endothelial cells) and Figure 2 Cell cycle profiling of post-pneumonectomy lung CD31 + endothelial cells obtained by enzymatic digestion and anal...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " Global gene expression patterns in the post-pneumonectomy lung of adult mice" ppt
... anti-inflammatory transcriptomic pattern observed during lung regeneration in this study, another recent study describes up-regulation of select inflammatory cytokines (Hmgb1 and INF -y) during ... -1.5 for the time-independent anal- ysis; genes with an S-score ≥ 3.0 or ≤ - 3.0 (P ≤ 0.003) for the time-dependent analysis), Ingenuity Pathway Analysis (IPA) version 2.0 (Ingenuity ® Syste...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo" potx
... for initiating early leukemogenesis in vivo. This supports the current limiting dilution cloning strategy as an appropriate tool for investigating HTLV-1-associated oncogenesis in naturally infected ... gnificantly distinct cel l cycle distributions between in vitro and in vivo infected clones and, surpris- ingly, also between uninfected clones derived from in vitro versus in...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: "Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling" pot
... changes in a mouse joint instability OA model [78], suggesting a role for increased RUNX2 expression in OA pathogenesis. An important role for RUNX2 in OA pathogenesis is supported by our microarray data. ... judged by genetic studies [27]. Interestingly, many of the candidate susceptibility genes for OA identified by genetic screening approaches have bone-related functions, fur...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challeng" ppt
... changes in multiple cytokine genes (12 out of 61 genes; 19.7 %) that showed a high level of expression in contrast to only few cytokine genes (4 out of 322 genes; 1.24 %) that showed increased expression ... pathogenesis of arthritis involves not only lymphoid cells, but also myeloid- lineage cells [29-31]. Therefore, to fully understand the expression of disease-relevant genes w...
Ngày tải lên: 12/08/2014, 18:20