Báo cáo y học: "Attenuation of acute lung inflammation induced by cigarette smoke in CXCR3 knockout mice" pps

... importance of CXCR3 in CS -induced lung inflammation by using CXCR3 KO mice. In conclusion, our study shows that CXCR3 regulates CS -induced lung inflammation via recruitment of CD8+ T cells into the lung ... of CXCR3 gene in mice significantly prevented the lung inflammation induced by exposure to CS. CXCR3 may be a key factor in CS -induced pul...

Ngày tải lên: 12/08/2014, 14:20

... animals. Lung injury was induced by an average number of 4.1 ± 0.4 lung lavages (lavage volume, 2071 ± 189 ml). Epinephrine was adminis- tered at a rate of 0.04 (0.02–0.06) µg/kg/minute to maintain ... the initiation of HFOV involves lung recruit- ment maneuvers, typically performed by increases of CDP in steps of 2–5 mbar up to 40 mbar [5-8]. Although increases of t...

Ngày tải lên: 12/08/2014, 23:24

... was reduced by HFOV only. Oxygen delivery was unchanged when P mean increased, independent of the ventilatory mode used (Table 2). Discussion Lung recruitment procedures by incremental increases of lung volumes ... The findings of an HFOV initiation protocol by stepwise increases of CDP can therefore only be compared with the used lung recruitment strategy by PCV with P...

Ngày tải lên: 12/08/2014, 23:24

... basis of patient history, physical exam- ination, routine laboratory examination, and chest radio- graphic findings [2,3]. However, interpretation of these parameters is often limited by a c ertain ... pressure of oxygen/fraction of inspired oxygen. Figure 1 Correlation of extravascular lung water (EVLW) measured by single transpulmonary thermodilution and by postmortem lun...

Ngày tải lên: 13/08/2014, 21:21

... vein in all 8 animals and in the distal part of the vein in 7 of the 8 animals. Edema (Grades 1-3) was found in the proximal part of the vein in 6 of the 8 animals and in the distal part of ... University. Drugs Navelbine ® Injection (VNR) and Adriacin ® Injec- tion (DXR) were kindly provided by Kyowa Hakko Kirin Co. (Tokyo, Japan). A 10 mg/mL vial of VNR w...

Ngày tải lên: 26/10/2012, 09:57

... cysteine biosynthesis found in the chloro- plasts, cytosol and mitochondria of plants [57]. In addition, the evolutionary history of 12 Calvin cycle enzymes shows that plant proteins encoded by ... Large- scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol 2007, 3:89. 43. Huang B, Gudi R, Wu P, Harris RA, Hamilton J, Popov KM: Isoen- zymes of...

Ngày tải lên: 09/08/2014, 20:21

... After evaluation of the medication by the physician responsi- ble, sertraline was replaced by 75 mg of venlafaxine and exfoliative cytology of the ulcer was performed. Exfoliative cytology of the lesion ... ulcers. In a review of 200 patients investigating the adverse effects of drugs in the oral cavity, Smith and Burt- ner observed dry mouth in 80.5%, dysgeusia in 47....

Ngày tải lên: 11/08/2014, 20:20

... study using the Mefar technique we demonstrated cross tachyphylaxis between capsaicin and citric acid challenge. Since in man these two modalities probably act by distinct sig- nalling pathways ... effects of diphenhydramine on the citric acid aerosol -induced cough response in humans. Int J Clinical Pharmacol Ther Toxicol 1991, 29:218-222. Figure 4 (A) Bland Altman plot of intra-d...

Ngày tải lên: 13/08/2014, 10:20

... filling pressures increase as an effect of cardiac dysfunction. In our study, lung dysfunction, reflected in impaired oxygenation index and mechanics, was the cause of approximately every third ... levels of creatine kinase isoenzyme increased in all high-volume groups and stayed stable in moderate-volume pigs (time × volume P = 0.006; Table 4). Discussion The main finding of...

Ngày tải lên: 13/08/2014, 20:21

... at days 1 to 2 and at days 3 to 5 after diagnosis of shock. Circulating leukocyte immunophenotyping was systematically performed by flow cytometry. The following leukocyte subsets were analyzed: ... mHLA-DR staining by flo w cytometry in one patient and one volun- teer are presented in Figure 1a. The following lymphocyte subsets were analyzed: total T lymphocytes (CD45 + CD3 + ), CD...

Ngày tải lên: 13/08/2014, 21:21