Báo cáo y học: "Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study" pdf

... derangement in the 200 mM α,β- MeATP-treated lungs. Bars = 100 μm in the upper panels, and = 50 μm in the lower panels. B. Immunohistochemistry of the P 2Y 2 and P 2Y 4 receptors. P 2Y 2 and P 2Y 4 receptors ... fluid status in the lung, the lung edema caused by ATP might be another mechanism of VILI. The antagonism of ATP- P 2Y signaling by PPADS block...

Ngày tải lên: 12/08/2014, 14:20

... inflammation/ infection and BPD The initial description of BPD by Northway, Rosan, and Porter [16] identified barotrauma and oxygen exposure as the causes of airway injury, fibrosis, and emphysema ... cells to the lungs and pro-inflammatory cytokine production has been identified as common to both oxidant injury and barotrauma in the lungs of the adult and the...

Ngày tải lên: 12/08/2014, 18:20

... seem to play an important role in PN injury and polyneuropathy [5-7]. The diameters and blood flow velocity of the femoral arteries are significantly reduced in the paralytic site [1]. The femoral ... surface of the cylindrical inner cavity of ANs. The borders long of the ref- erence cylinder are given by 2 ∏r and h. Thus, the surface area of the reference plane...

Ngày tải lên: 10/08/2014, 10:20

... did the animals studies, the molecular analysis, statistical analysis and drafted the manuscript. SGK did research design, molecular analysis and manuscript development. JJP did animal care and ... (GRP), the Women and Infants Research Foundation and Fisher & Paykel Healthcare, Auckland, NZ. The authors would like to thank Megan McAuliffe and Amy Whitescarver for the...

Ngày tải lên: 12/08/2014, 11:22

... furthering the understanding of stem cell biology. Interestingly, through more in-depth analyses, the known distribution of CD34 in vivo has recently expanded to include many of the key cell types ... growth factors and cytokines. For example, CXCR4/CXCL12, a general inflammatory chemokine receptor and chemok- ine ligand, is the only known chemokine receptor expressed by HSCs a...

Ngày tải lên: 08/08/2014, 21:20

... (Fluoroskan Ascent, ThermoLab systems, Helsinki, Finland) and Thrombinoscope software (Thrombinoscope BV, Maas- tricht, the Netherlands) as previously described [16]. CD4 cell counts were analyzed ... long-term use of antiretroviral therapy with or without abacavir AIDS Research and Therapy 2010, 7:9 Jong et al. AIDS Research and Therapy 2010, 7:9 http://www.aidsrestherapy.com/conte...

Ngày tải lên: 10/08/2014, 05:21

... primarily performed the compression experiments, and participated in the data analysis and checking the manuscript. YMC helped conceive of the study, provided animals for the study, and participated ... drafting the manuscript. All authors read and approved the final manuscript. Acknowledgements This study was sponsored by grants from the Muscular Dystrophy Society...

Ngày tải lên: 10/08/2014, 10:20

... a nerve and its presence or absence may be strongly influ- enced by anesthesia. Second, the type of chan ge to be expected in the CMAP depends on the mechanism of injury. Early changes in the velocity ... significant and better able to classify the changes in the CMAP than the velocity. This is different from the case of a purely compressive injury where the amplitu...

Ngày tải lên: 10/08/2014, 10:20

... withholding short- and long-act- ing b-agonists (for ≥8 and ≥12 hours, respectively), short- and long-acting theophylline preparations (for ≥24 and ≥48 hours, respectively) and antileukotrienes ... PLIFT study is the size and duration of the study that still pro- vides substantial data. Additionally, while not fully com- pensating, statistical techniques used in the analysis...

Ngày tải lên: 12/08/2014, 13:22

... Following sternotomy, the trachea and pulmon- ary artery were cannulate d and the heart and lungs removed en bloc. The right main bronchus, the pulmon- aryarteryandthepulmonaryveinsweretiedwitha ligature ... 1 day 3 day 7 day 14 day 21 day 0 1 2 3 4 5 1 day 3 day 7 day 14 day 21 day 0 1 2 3 4 5 1 day 3 day 7 day 14 day 21 day 0 1 2 3 4 5 1 day 3 day 7 day...

Ngày tải lên: 12/08/2014, 13:22