Báo cáo y học: " Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin" potx

... bleomycin 6 in bleomycin6 in bleomycin 6 in bleomycin- -induced lung induced lung induced lung induced lung inflammatory changes in mice inflammatory changes in miceinflammatory changes in mice inflammatory ... bleomycin bleomycinbleomycin bleomycin- -induced pulmonary inflammation in the rat induced pulmonary inflammation in the ratinduced pulmonary i...

Ngày tải lên: 12/08/2014, 14:20

... acquired and analyzed using Becton Dickinson BD LYSYS II and Cyto- metric Bead Array (CBA) software (San Jose, CA). Levels of cytokine and chemokine in BAL fluid The levels of cytokines and chemokines ... respiratory epithelial cell line with rhinovims. Induc- tion of cytokine release and modulation of susceptibility to infection by cytokine exposure. J Clin Invest 1995, 9...

Ngày tải lên: 12/08/2014, 18:21

... plays a role in airway inflam- mation. Knockout of NPRA in mice resulted in less lung inflammation [11]. Inhibition of NPRA by small inferfer- ing RNA against NPRA attenuated lung inflammation in ... containing pVD. Parameters of airway inflammation, such as airway hyperreactivity, proinflammatory cytokine levels, eosinophil recruitment and lung histopathology wer...

Ngày tải lên: 12/08/2014, 14:20

... between systemic inflammation and symptoms of depression and fatigue in patients with mainly moderate and clinically stable COPD using a range of inflammatory biomarkers, 2 depression and 2 fatigue ... substantial impairment in quality of life [8]. The association between symptoms of depression and fatigue and systemic inflammation has been examined in depth in...

Ngày tải lên: 12/08/2014, 13:22

... inflammation initiated by smoking leads to a changes in both – airways and lung parenchyma. The main known contribution of smoking is activation and recruitment of inflammatory cells to the lungs ... After washings in PBS, the slides were incubated with biotinylated secondary anti- body (Santa Cruz, USA) for 30 min. Followed by wash- ings in PBS, slides were incubated with...

Ngày tải lên: 12/08/2014, 15:21

... airway and at the ventilator, in a research study with a test lung. Methods The subjects were infant, adult and pediatric test lungs. In the test lung model, lung compliances were set to normal and ... Pediatric pulmonary and Intensive Care and Director of Pediatric ICU, Dhahran Health Center, Saudi ARAMCO, Saudi Arabia 2 Director of Respiratory Care and Biomedical E...

Ngày tải lên: 12/08/2014, 20:20

... types, when activated, appear to play a central role in promoting and maintaining the dis- ease process [4,5], for example by producing certain sets of cytokines that influence the quality and ... study, samples of knee-joint SM, inguinal LNs, and spleen were obtained from rats killed at six time points: day 0, 6 hours, day 1, day 3, and day 6 of AIA. Cytokine protein analysis...

Ngày tải lên: 09/08/2014, 06:22

... containing syncytia in response to focal areas of virus infected cells. Plates were fixed and stained 3 days later and examined for plaques of syncytia. Syncytium formation and inhibitors of N-linked ... virus induced syncytia. While virus induced syncytia were only seen in the dCAT-1 trans- fectants, a different panel of virus isolates was capable of efficiently infecting...

Ngày tải lên: 13/08/2014, 06:20

... smoke (CS) induced -lung inflammation in mice. CXCL10/IP-10 (IFNγ-inducible protein 10) and CXCL9/Mig (monokine induced by IFN-γ) are up-regulated in CS-induced lung injury and may attract T-cell ... CS initiates the infiltration of innate and adaptive inflammatory cells into the airways and the lung parenchyma and further destroys the alveolar structure [2- 6]. The ro...

Ngày tải lên: 12/08/2014, 14:20

... mice developed significant increases in lung resistance in response to increasing 1 Attenuation of antigen-induced airway hyperresponsiveness and inflammation in CXCR3 knockout mice Yi ... significantly higher in OVA-sensitized and challenged WT mice than in CXCR3 KO mice (figure 1B). Semiqualitative analysis of inflammation in the lung by hist...

Ngày tải lên: 12/08/2014, 14:20