Báo cáo y học: " Expression analysis of asthma candidate genes during human and murine lung development" pps

... Melén et al.: Expression analysis of asthma candidate genes during human and murine lung development. Respiratory Research 2011 12:86. Submit your next manuscript to BioMed Central and take full ... associated with asthma. To test this hypoth esis, we investigated the role of a well-defined set of asthma susceptibility genes during human and murine lu...

Ngày tải lên: 12/08/2014, 13:22

... comprise 21% of human genes and 27% of mouse genes, respectively, and the CDSs comprise 79% of human genes and 73% of mouse genes, respectively. These numbers served as the null hypothesis for ... below). Our analysis of the numbers of TEs in the human and mouse genomes is summarized in Tables 1 and 2, respectively. There are approximately 3.9 and 3.1 mil...

Ngày tải lên: 14/08/2014, 07:21

... No 6 Research article Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time ... production of hyaluronan in OA or RA may be decreased because of the reduced expression of HAS-1 and -2 messages. The elimination volume of hyaluronan may be increased...

Ngày tải lên: 09/08/2014, 01:24

... either side of the gap, and supports the placement of hap- Analysis of symmetrical region near the centromeric end of 15q to identify its likeliest arrangement in RP11Figure 6 Analysis of symmetrical ... both Prader-Willi and Angelman syndrome patients. Am J Hum Genet 1995, 57:40-48. 3. Wandstrat AE, Schwartz S: Isolation and molecular analysis of inv dup(15) and con...

Ngày tải lên: 14/08/2014, 07:21

... orthologs; and SOM analysis of established primary PPAR target genes, clusters III and IVFigure 7 (see previous page) SOM analysis of established primary PPAR target genes, clusters III and IV. The genes ... conserved area of intron 1. In silico analysis of selected primary PPAR target genesFigure 3 (see following page) In silico analysis of selected primary PPAR t...

Ngày tải lên: 14/08/2014, 08:20

... (fz2) [57] and the wingless modifier rotund (rn), were found [58] (Tables 3 and 4). Equally interesting, Table 1 Summary of Gene Ontology overrepresentation analysis of genes regulated by insulin GO ... represented. Table 2 Summary of Gene Ontology overrepresentation analysis of genes regulated by the wingless pathway GO term category Transcription (45) AS (32) AS only (38...

Ngày tải lên: 14/08/2014, 21:20

... Moffatt MF: A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. Clin Exp Allergy 2009, 39(12):1875-1888. 191. ... innate and adap- tive immunity. Lung plasmacytoid DCs (pDCs) express uniquely high levels of TLR7 and TLR9 that suppress the allergic response and regulatory lung DCs give r...

Ngày tải lên: 11/08/2014, 03:20

... activation of proinflam- matory cytokines? In addition, it would be of interest to identify the type of cells exhibiting elevated PARP activity – for instance, perhaps by double staining with leukocyte markers. ... found increased expression of IL-1β, IL-6, and keratinocyte-derived chemokine in the lung homogenate and found an increased number of pulmonary leucocytes in mice...

Ngày tải lên: 13/08/2014, 11:23

... extraction and array analysis. For each array sample, the RNA was prepared from the purified thymocytes. The thymocytes were processed by using the RNEasy Mini Kit (Qiagen, Valencia, CA). Quality and ... Real-time RT-PCR analysis reveals increased levels of mRNA expression of BAFF and APRIL in aged thymocytes. BAFF and APRIL are both involved in maturation and survival...

Ngày tải lên: 03/11/2012, 11:35

... x-3 hydroxy fatty acids, respectively. 2080 T. Kitazume et al. (Eur. J. Biochem. 269) Ó FEBS 2002 Kinetic analysis of hydroxylation of saturated fatty acids by recombinant P450foxy produced by an Escherichia ... fundamentally as described previously [15] by gas chromatography (GC) and GC-electron impact-mass spectrometry (GC-EIMS). Prior to analysis, the carboxyl group of the produ...

Ngày tải lên: 08/03/2014, 22:20