Báo cáo y học: " A promoter SNP rs4073TA in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode" docx

... sion are incre ased in the BAL fluid and the alveolar macrophages of patients with IPF [9]. An animal study also confirmed the role of IL -8 in pulmonaryfibrosisbydemonstrating that bleomycin- induced ... 270(15):3251-3262. doi:10.1 186 /1465-9921-12-73 Cite this article as: Ahn et al.: A promoter SNP rs4073T> ;A in the common allele of the interleukin...

Ngày tải lên: 12/08/2014, 13:22

... FAM-CACTTATCTGTAGAGCTT-MGB SNP4 F CTGGCAATTCTGCCTTGTTTCAG SNP4 allele1 VIC- CCGAAGATAAAAGAATC-MGB SNP4 R GGATTACAGCCGTGAGCCA SNP4 allele2 FAM- CGAAGATAGAAGAATC-MGB SNP5 F AAGCTGAGGCAGGAAGATCAC SNP5 allele1 ... ACGGAAGAAAAGATTT-MGB SNP1 1R AATAAAGTGGCAGAGGATACGAGTACT SNP1 1 FAM-ACGGAAGAAAACATTT-MGB SNP1 2F AATTGTCTCCCAGTGCATTTTGC SNP1 2 allele1 VIC-CTGCCAACTCTGGCTG-MGB SNP1 2R T...

Ngày tải lên: 09/08/2014, 07:20

... this case report and any accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Acknowledgements We sincerely appreciate the superb assistance ... patient, including non-surgical measures such as the use of arti- ficial tears and moist gauze covering of the eyes to pre- vent drying of the cornea. Early eye...

Ngày tải lên: 10/08/2014, 23:22

... between aa122 and aa123 [15,16], 3-aa insertion between aa123 and aa124 [16], 1-aa insertion between aa121 and aa122 [20], 3-aa insertion between aa1 18 and aa119 [ 18] , 2-aa deletion from aa110 to aa111 ... Alexopoulou A, Baltayiannis G, Jammeh S, Waters J, Dourakis SP, Karayiannis P: Hepatitis B surface Antigen variant with multiple mutations in the α determinant in an Agammagl...

Ngày tải lên: 12/08/2014, 04:20

Ngày tải lên: 13/08/2014, 01:20

... distance difference matrix analysis revealed binding sites associated with up-regulation of p53 target genes, including GATA-1 and STAT 5A. Physical co-occurrence of a binding site for GATA-1 and ... additional data are available with the online version of this paper. Additional data file 1 is a DDM-MDS plot of an artificial example, demonstrating the power of the...

Ngày tải lên: 14/08/2014, 07:21

... on the problem, delineated the structures and mechanisms of all of the major players in this pathway. Dan's enthusiasm for this new foray into cell biology - a field seemingly light years removed ... it's the support we give the stranger, the casual scientific acquaintance, that has the greatest influence. When a senior scientist, especially one of any emin...

Ngày tải lên: 14/08/2014, 07:22

... and homeostasis. Notch binds to a family of transmembrane ligands, resulting in cleavage of the receptor, translocation of the intracellular domain to the nucleus and activation of a number of ... than inhibiting ubiquitination, Numb can enhance the degradation of Gli1 by Itch - again pointing to a rather specific effect of Numb on the stability of p53. Rathe...

Ngày tải lên: 14/08/2014, 08:21

... AGATCGTTGCACATCGGCCCAATATATAATACATATAACAACTAAACGATCAAAACGATC R32F3 AGATCGTTGCACATCGGCCCAATATATAATACATATAACAACTAAACGATCAAAACGATC WT AGCAATGAGGCTGTTTTTGCGAAGTAACTCGAC TAAACCGCGATCGCATTGT R32F3 AGCAATGAGGCTGTTTTTGCGAAGTAACTCGACCGAGTAAC ... because they are transmitted via males only, and that flies carrying a mutation can easily be singled out on the basis of the eye phenotype. The...

Ngày tải lên: 14/08/2014, 14:21

... 5¢-CAAGGACGTTCGATGCA CTTCCAAAAAACATATAAT-3¢; Oligo II, 5¢-CAAT GTAGTATTAAAAAGTAGTAGTTAAAAGC-3¢; Oligo III, 5¢-GTTTTTATCCGATGCAAATTTTTGCTTTGT GATTG-3¢. The reaction was performed in 20 lL DNA-binding buffer ... is a DNA-binding protein and it interacted specifically with one of the cis acting elements of the Arabidopsis CaM5 gene (AtCaM5) promoter. The binding of p40...

Ngày tải lên: 18/03/2014, 01:20