Báo cáo y học: " Involvement of mast cells in monocrotalineinduced pulmonary hypertension in rats" pot

... distribution in chronically hypoxic animals. J Appl Physiol 1977, 42:174-8. doi:10.1186/1465-9921-12-60 Cite this article as: Dahal et al.: Involvement of mast cells in monocrotaline-induced pulmonary hypertension ... a role in cardiac remodeling in hypertension- induced heart failure. J Mol Cell Cardiol 2008, 45:779-86. 15. Okayama Y, Ra C, Saito H: Role of mast ce...

Ngày tải lên: 12/08/2014, 13:22

... that in Akt and the discrep- ancy of cell types involved in our study suggested the use of a single model may be limiting in terms of providing adequate generalizable information. Conclusion Using ... macrophage-induced cytotoxicity, and induction of vas- cular and epithelial hyperpermeability [17,18]. The expression of eNOS may be induced by calcium-dependent binding of cal...

Ngày tải lên: 13/08/2014, 08:20

... CLDN- 7-associated protein may not be correspondingly increased. Therefore, addition of CLDN-7 to 293T cells can only partially increase levels of HIV infectivity, approximately 10% of that of LNCaP cells. Because ... percentage of Env(-) HIV present in patients, which may be able to infect some types of CD4(-) cells, such as neurons and glial cells. The infection of bra...

Ngày tải lên: 13/08/2014, 09:21

... exclusion of Trypan blue. Immunofluorescence staining of cells Staining for dual-color immunofluorescence was performed on aliquots of 1 to 2 × 10 5 cells by means of a combination of indi- rect ... first 6 days, PMN cells and typical inflammatory mono- cytes did not increase until days 9 to 12 and days 12 to 14, respectively. The delayed appearance of MHC II - cells (main...

Ngày tải lên: 09/08/2014, 10:22

... 18:55 http://www.jbiomedsci.com/content/18/1/55 Page 7 of 8 RESEARC H Open Access Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects Hyo-Soon Jeong 1 , Seung Hoon Lee 1 , Hye-Young Yun 1 , Kwang Jin Baek 1 , ... by freezing and thawing. After quantifying t he protein levels of the lysate and adjusting the protein concen- trations with lysis...

Ngày tải lên: 10/08/2014, 10:20

... Na 3 VO 4 ) containing protease inhibitors (1 mM phenylmethylsulfonyl fluoride, 0.2 trypsin inhibitory units/ml aprotinin, and 20 µg/ml leupeptin). The lysates were centrifuged for 10 minutes at 4°C ... pathways [11]. For example, integrin α6β4, a laminin receptor, is incorporated in lipid rafts through palmitoylation at cysteine in the membrane-proximal segment of β4 tail, which su...

Ngày tải lên: 10/08/2014, 10:20

... col- lections of mucinous material con taining varying combi- nations of mucopolysaccharides and mucoproteins within the adventitial layer of the artery. The cysts exert extrinsic pressure on the ... adventitial cyst to become symptomatic involves a sufficient increase of the pressure within the fluid-filled cyst during muscle exertion, thus resulting in haemodynamically significa n...

Ngày tải lên: 11/08/2014, 12:20

... Pieske B, Schro- der F, Molkentin JD, Drexler H, Wollert KC: Inhibition of cal- cineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci USA ... 2002, 283(1):L144-155. 27. Golovina VA, Platoshyn O, Bailey CL, Wang J, Limsuwan A, Sweeney M, Rubin LJ, Yuan JX: Upregulated TRP and enhanced capacita- tive Ca 2+ entry in human pulm...

Ngày tải lên: 12/08/2014, 14:20

... for eosinophilia and T H 2-type cytokines in bronchial lymph nodes (NK1.1 + , αβ T cells) [34 • ]. Protective responses to pulmonary injury require γγδδ T cells In contrast, several lines of evidence ... encephalitis [25]. Intriguingly, the invariant TCR expressed by all of these cells is nearly identical to that of the γδ T cell population colonizing the murine epi- dermis,...

Ngày tải lên: 12/08/2014, 18:20

... loaded. Determination of active form of RhoA in BSM The active form of RhoA, GTP-bound RhoA, in BSMs was measured by RhoA pull down assay. In brief, bronchial tissues containing the main and intrapulmonary ... muscle contraction including airways is mainly regulated by an increase in cytosolic Ca 2+ concentration in myocytes. Recently, additional mechanisms have been suggeste...

Ngày tải lên: 12/08/2014, 18:21