Báo cáo y học: " Differentiated transplant derived airway epithelial cell cytokine secretion is not regulated by cyclosporine" pdf

... Access Differentiated transplant derived airway epithelial cell cytokine secretion is not regulated by cyclosporine Timothy Floreth † , Eric Stern † , Yingli Tu, Randi Stern, Edward R Garrity Jr, Sangeeta ... actin. Conclusion: Transplant derived differentiated airway epithelial cell IL-6, IL-8, and TNF-a secretion is not regulated by cyclosporine...

Ngày tải lên: 12/08/2014, 13:22

... therapy. Thus, in this study the synovial expression of IL-15 in RA was not consistently influenced by TNF blockade, being apparently independent of TNF expression in the synovium. Consequently, ... fac- tor alpha blockade reduces the synovial cell infiltrate early after initiation of treatment, but apparently not by induction of apoptosis in synovial tissue. Arthritis Rheum 2003, 4...

Ngày tải lên: 09/08/2014, 07:20

... virion core is released into the cyto- plasm. This coneshaped core consists of the capsid (CA- p24) protein containing the RNA genome and viral enzymes. This core is dissolved only partially during ... drop in GFP-expressing cells is therefore caused by direct RNAi-inhibition of the reporter transcript, and not by targeting of the incoming RNA genome. Discussion We have not obse...

Ngày tải lên: 13/08/2014, 09:20

... air- way epithelial lining fluid. was calculated at 5.3 ± 2.1 μg/ml. Statistical analysis For normally distributed data, one-way analysis of var- iance (ANOVA) was used for multiple comparisons, ... fluorescent dye (e.g., IRDye® 800), and detected by using the Odyssey Imaging System. Densito- metry was then performed to quantify SPLUNC1 pro- tein levels. Intracellular SPLUNC1 protein of h...

Ngày tải lên: 12/08/2014, 11:23

... on airway cell apoptosis; TUNEL techniqueFigure 3 Effect of Cl 2 exposure on airway cell apoptosis; TUNEL technique. A: Control mouse airway, showing baseline airway epithelial cell apoptosis ... sections and by scoring of airway fibrosis on Picrosirius red stained tissue sections. Goblet cell numbers were assessed by light microscopy and standard morphometric techniqu...

Ngày tải lên: 12/08/2014, 15:21

... Ltd (Print ISSN 1364-8535; Online ISSN 1466-609X). This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved ... were quantified by ELISA (R&D Systems, Wiesbaden, Germany and IBL GmbH, Hamburg, Germany, respectively). The concentration of the complement fragment C3d was determined...

Ngày tải lên: 12/08/2014, 19:22

... protein was detected by immunoblot analysis in the two HTLV-1- transformed T -cell lines but not in the ATLL -derived T -cell line (data not shown). Cell viability was assessed by the water-soluble ... T -cell malignancy caused by infection of mature CD4 + T cells by human T -cell leukemia virus type 1 (HTLV-1) [1-3]. ATLL is clinically and hematologically subclassified...

Ngày tải lên: 13/08/2014, 05:21

... quality of care are mostly about ICUs without 24-hour intensivist coverage. The present study is not informative on this subject. Finally, hospital mortality is only a small part of quality of ... 30:895-901. Key messages • In this study in three intensivist-led ICUs, daytime was defined by the time period in which intensivists are rou- tinely present in the unit and off hours was de...

Ngày tải lên: 13/08/2014, 16:21

... results should only be viewed as hypothesis-generating given the retro- spective design of the study’ [1]. We are concerned that this potentially divisive hypothesis is not founded on sound ... confounding factors in this study that are not addressed by studies such as this. We call for attention to remain focused on the major hurdles facing all physicians in modern-day intensiv...

Ngày tải lên: 13/08/2014, 20:21

... this is not the case with anticholinergics. 23 Salbutamol is a potent broncho- dilator, but it could also inhibit cysteinyl leukotriene synthesis by the airway cells. 24 Asthma is a complex disorder ... presence of airway hyperresponsiveness. Methacholine chloride is a synthetic derivate of acetylcholine, which is a parasympa- thetic neurotransmitter that is very important...

Ngày tải lên: 08/08/2014, 21:20