Báo cáo y học: " Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis" pot

... be induced by proinflammatory cytokines, such as TNF-a,andIL-1b . The immunohistochemistry method applied in our study revealed a positive staining of iNOS Figure 6 Ef fects of adrenomedullin ... may modulate the inflammatory process through regulation of the secretion of cytokines; we analyzed the lung levels of the pro -inflammatory cyto- kines TNF-a and IL-1b. A substantial increa...

Ngày tải lên: 12/08/2014, 13:22

... inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi ’s sarcoma presenting as acute intestinal obstruction: a case report Jyotirmoy ... visceral involvement. Conclusions IRIS-KS may occur in HAAR- naïve individuals with AIDS-related KS. Gastrointestinal KS may present with a sudden increase in size leading to acute inte...

Ngày tải lên: 10/08/2014, 23:22

... increase in the levels of circulating cytokines, and in particular TNF-α during the process of aging. Sec- ond, vascular aging is associated with the increased pro- duction of reactive oxygen species ... Factors Pro-/Anti -inflammatory Selected Target Genes Alterations with Aging NF-κB Pro -inflammatory MCP-1, ICAM-1, NOS2 Increased HIF-1α Anti -inflammatory VEGF, SDF-1 Decreas...

Ngày tải lên: 11/08/2014, 08:22

... efficacy of PPIs and H2RAs in the primary prevention of clinically relevant endpoints, such as bleeding and perforated NSAID ulcers, remains unproven. The discovery of the isoenzymes cyclooxygenase ... Furthermore, in elderly patients with a recent history of bleeding NSAID ulcers, sec- ondary prevention (preventing recurrent bleeding) with a selective COX-2 inhibitor seems comparable...

Ngày tải lên: 09/08/2014, 10:20

... Ankylosing Spondylitis Disease Activity Index and the Bath Ankylosing Spondylitis Functional Index. These quantitative traits will require even larger numbers of cases to study, since they will ... developing ankylosing spondylitis (AS) but also of its severity [1], as assessed by radiographic measures or by self- administered questionnaires such as the widely used Bath Ankylosing Spondylitis...

Ngày tải lên: 09/08/2014, 14:20

... albeit involving different dinucleotides. The same periodic RR/YY dinucleotide frequency is seen in human and mouse promoters, but interestingly the medaka fish Oryzias latipes displays a strong ... S1B in Additional file 1; see Materials and methods) and found that mainly purine- purine (RR) and pyrimidine-pyrimidine (YY) dinucle- otides contribute to the periodic signal (Figure 1a, inse...

Ngày tải lên: 09/08/2014, 20:22

... of NVP- induced rash were reportedly observed mainly in patients whose CD4 counts were over 250 cells/μl [29]. Accord- ingly, nearly all of patients in our study started NVP-con- taining regimen ... HLA-Cw*04 is associated with rash in nevirapine treated Thais. Future screening of patients' HLA may reduce the number of nevirapine-induced rash cases, and patients with alleles...

Ngày tải lên: 10/08/2014, 05:21

... strength, leading to pain, deformity, and pathological fractures [4]. The etiology of fibrous dysplasia has been linked to a muta- tion in the G s a gene, leading to an increase in cyclic adenosine monophosphate, ... effects important in the pathogenesis of fibrous dysplasia [5]. An intra-muscular myxoma is usually a solitary lesion that is not generally associated with any other cl...

Ngày tải lên: 10/08/2014, 23:21

... are b alanced by an array of anti -inflammatory cyto- kines. The coagulation pathway is also activated by LPS- mediated signaling and further regulated by the cyto- kines, inducing the production ... (TLR-4) signaling pathway that results in translocation of nuclear factor-B(NF- B) and production o f inflammatory cytokines. The result is a production of pro -inflammatory cytokines tha...

Ngày tải lên: 11/08/2014, 08:22

... underestimated. Competing interests The authors declare that they have no competing interests. No financial support from any company was received in the performance of this study, nor do any authors have equity ... to intensive preoperative screening, including ultrasonography and if necessary angiography. Introduction The management of complex pelvic fractures is a major challenge in tra...

Ngày tải lên: 11/08/2014, 10:23