Báo cáo y học: " Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study" potx

... al.: Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study. Respiratory Research 2011 12:37. Miniati et al. ... lacking transmembrane and cytosolic domains, acts as a decoy receptor for R AGE ligands in the extracellular compart- ment, and is believed to afford p...

Ngày tải lên: 12/08/2014, 13:22

... joint disease; RA = rheumatoid arthritis; RAGE = receptor for advanced glycation end products; sRAGE = soluble receptor for advanced glycation end products. Arthritis Research & Therapy Vol ... of soluble receptor for advanced glycation end products (soluble RAGE) in blood and synovial fluid (SF) of rheumatoid arthritis (RA) patients and in...

Ngày tải lên: 09/08/2014, 06:23

... 2 Research article Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and ... Kurita-Nakamura Y, Matsui T, Yoshida T, Sato A, Imaizumi T: Elevation of soluble form of receptor for advanced glycation end products (sRAGE) in dia- bet...

Ngày tải lên: 09/08/2014, 13:22

... by binding DAMPs and other ligands and inhibiting leukocyte recruitment in a variety of acute and chronic inflammatory conditions [4]. Both esRAGE and sRAGE act as decoy receptors for the ligand HMGB1 ... local cytokines. Sepsis HMGB1 propagates inflammatory responses and is a significant RAGE ligand in the setting of sepsis and acute inflammation. HMGB1 is an apparent...

Ngày tải lên: 18/06/2014, 15:20

... β-pleated sheet fibrils of amyloid and advanced glycation end products (AGEs) [15]. AGEs are the products of nonenzymatic glycation and oxidation of proteins that form with aging, diabetes and ... Silman AJ: Baseline levels of C-reactive protein and prediction of death from cardiovascular disease in patients with inflammatory pol- yarthritis: a ten-year followup st...

Ngày tải lên: 09/08/2014, 10:20

... cartilage and bone in the affected joints. Synovial hyperplasia is a hallmark pathology of RA, and fibroblast-like synovio- cytes (FLS) play a critical role in RA pathogenesis by producing pro-inflammatory ... Bucciarelli LG, Wendt T, Sakaguchi T, Lalla E, Qu W, Lu Y, Lee L, Stern DM, Naka Y, Ramasamy R, Yan SD, Yan SF, D’Agati V, Schmidt AM: Blockade of receptor for advanc...

Ngày tải lên: 12/08/2014, 17:22

... of a charged and linear lysine for a uncharged and branched asparagine at position 103 result in a drastic change in the chemical environment in the proximity of the mutation. This has mainly ... mutant would be expected to have favorable interactions with the mutant asparagines side chain, thereby compensating for resistance caused by stabilization of the mutant enzyme...

Ngày tải lên: 18/03/2014, 01:20

... ligands mRNA expression increased in the aging thymus. The CCR5 ligands, CCL4 and CCL5, increase in the thymic parenchyma as revealed by the age-associated increases in the staining of thymocytes ... perivascular space in the septa and capsule. Ad- ditionally, these cells were visualized in the subcap- sulary region of aged thymi and inside the thymic aged parenchyma in...

Ngày tải lên: 08/08/2014, 18:20

... create a model for female offending. Many of the researchers point out that the origins of male offending cannot simply be transferred to female offend- ing without necessary investigation as ... childhood physical, psychological and sexual abuse and that conduct problems were evident early on (lack of graduation). In adulthood, there appears to be a tendency toward poor mental he...

Ngày tải lên: 11/08/2014, 17:20

... predisposing injury and in the absence of heart failure [7]. The hallmarks of ALI are increased capillary permeability, interstitial and alveolar edema, influx of circulating inflammatory cells, and for- mation ... resistant to the damage and leak induced by VEGF or inflammation [14]. Existing data suggest that VEGF and angiopoietins act in a very complementary and coordin...

Ngày tải lên: 12/08/2014, 16:20