Báo cáo y học: " Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4" potx

... 4). Discussion The results of our ex vivo studystronglysuggestacon- trasted picture of T cell activation in allergic rhinitis and asthma, with distinct patterns of Th1, Th2 and Treg profiles and expression ... objective o f this study was therefore to compare the pattern of T cell activation between allergic rhinitics and asthmatics upon allergen stimulati...

Ngày tải lên: 12/08/2014, 13:22

... concentration of protein, the binding enthalpy of intact apoE4 was consistent with the sum of the enthalpies for the 22 kDa and 10 kDa derivatives, indica- ting that both NH 2 - and COOH-terminal ... domains bind to the emulsion surface [28]. At saturation, however, the enthalpy for intact apoE4 was similar to that of the 10 kDa fragment, suggesting that only the COOH-terminal dom...

Ngày tải lên: 08/03/2014, 09:20

... Krug RM: Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor. Virology 1995, ... developments, contributed to the interpretation of the findings and revised the manuscript. GM , contributed to and revised the manuscript. SB contributed to conception, interpretati...

Ngày tải lên: 11/08/2014, 21:21

... or secretory leukoprotease inhibitor, both of which protect tissue against the destructive action of neutrophil elastase at the site of inflammation. Our data suggests that the air- way epithelium ... increase in airway hyperresponsiveness to acetylcholine in the aprotinin-treated PBS compared to PBS bound to alum, but this increase was not statistically significant. These data demo...

Ngày tải lên: 12/08/2014, 15:21

... recognition of therapeutics to be endowed with anti-HIV activity and that mannose, but not complex-type glycan binding of chemotherapeutics to gp120, may result in a pronounced neutralizing activity ... properly cited. this respect, it cannot be excluded that the anti-HIV activity of GNA maize maybedue,notonlytoabinding to complex-type glycans present on HIV-1 gp120 but also to pote...

Ngày tải lên: 13/08/2014, 01:20

... variables of interest. Results: Study results reflect the complexity of factors that may promote or inhibit HIV transmission in conflict-affected and displaced populations. Within this setting, factors ... critical interpretation of the intellec- tual content and drafting of the paper. ZT and GM partic- ipated in the management of field level data collection. All authors h...

Ngày tải lên: 13/08/2014, 13:21

... analysis and interpretation of data and to drafting the article. AD contributed to analysis and interpretation of data and to drafting the article and provided statistical expertise. All investigators ... contributed to study conception and design and to analysis and interpretation of data and provided statistical expertise. FP contributed to the acquisition of data....

Ngày tải lên: 13/08/2014, 21:21

... receive TTA. The classical concept of "spec- ificity", defined as the probability of no TTA among those with minor injury, gives little information about "unnec- essary" strain to ... variation, including physiological "cut-off" values. Competing interests The authors declare that they have no competing interests. Authors' contributions KTL and OU conc...

Ngày tải lên: 13/08/2014, 23:21

... significant proportion of these Igs ingested in the colostrum is absorbed across the epithelial cells of the small intestine during the first few hours of life and transported via the lymphatic system ... determined by the concentration of Ig in the colostrum and the volume that is fed. There can be substantial variation in the concentration of Ig in colostrum of dairy...

Ngày tải lên: 07/08/2014, 17:22

... gain insight into the distinct pathology following HTLV-1 and HTLV-2 infection. Methods Cells 29 3T and HeLa-Tat cells were maintained at 37°C in a humidified atmosphere of 5% CO 2 in air in ... nuclear-localizing and shuttling phosphoprotein that acts post-transcriptionally by prefer- entially binding, stabilizing, and selectively exporting the unspliced and incompletely s...

Ngày tải lên: 12/08/2014, 23:22