Báo cáo y học: " Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats" pps

... for therapeutic intervention in pulmonary hypertension. Pharmacol Ther 2001, 92:1-20. 3. Rabinovitch M: Pulmonary vascular remodeling in hypoxic pulmonary hypertension. In Hypoxic Pulmonary Vasoconstriction ... migration in hyp oxia-induced pulmonary hypertension. We hypothe- sized that inhibition of systemic CXCR4 through admin- istration of AMD3100 wi ll inhib...

Ngày tải lên: 12/08/2014, 13:22

... epidemiologically or clinically useful prognostic information. Conclusions In summary, our analysis of CCR2-CCR5 haplotypes consisting of common combinations o f SNP alleles spanning those two ge nes has confirmed ... Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early H...

Ngày tải lên: 13/08/2014, 01:20

... having created an equal injury, the injury was sutured using 6-0 poly- glactin (vicryl). Then the air leakage and bleeding were controlled and the times of cessati on of the leakage and bleeding ... thoracotomy. An injury 5 mm in length and 2mm in depth was created in the left lung parenchyma using a scalpel. In the control group (Group I), no interventions were made for...

Ngày tải lên: 10/08/2014, 09:23

... CCR7 stainting. The staining intensity is strong. B was MMP-9 stainting. The staining intensity is strong. C was MMP-2 staining. The staining intensity is intermediate. Table 2 The correlation between ... cell malignancy. Stimulation of CCR7 by its ligand CCL21 induces migration and invasion of CCR7-expressing can- cer cells [7]. Furthermore, inhibition of the chemokine receptors, s...

Ngày tải lên: 10/08/2014, 10:21

... assisted in designing the review methodology, interpretation of the findings and in the drafting of the manuscript. RMS assisted in the interpretation of the findings and in the drafting of the manuscript. ... quality. The main limitations were with external and internal validity, selection and confounding biases. Although blinding and randomisation are considered to...

Ngày tải lên: 10/08/2014, 21:24

... study investigating two kinds of fetal type II cell injury, cell death and inflammatory response, which are both inducib le during hyperoxia, and whether rIL-10 may be effective in attenuating ... from injury induced by 65%-hyperoxia. Introduction Administration of high concentrations of oxygen is a therapeutic mainstay for premature infants with respi ra- tory distress syndrome s...

Ngày tải lên: 12/08/2014, 13:22

... study reinfusion rather than ultrafil- trate clamping because sieving may augment adsorption by increasing the effective surface area of the membrane by exposing more of the inner matrix of the ... Spaeth P, Schad H, Meisner H: Influence of combined zero-balanced and modified ultrafiltration on the systemic inflammatory response during coronary artery bypass graft- ing. J Cardioth...

Ngày tải lên: 12/08/2014, 18:21

... dose response by measuring free magnesium lev- els in brain tissue for the effects of magnesium therapy in sep- sis-induced brain injury. Conclusion This investigation shows that sepsis increases ... model of sepsis induced by an intraperitoneally inserted infected fibrin– thrombin clot. Methods One hundred and twenty-six male Sprague–Dawley rats weighing 320–440 g were used in th...

Ngày tải lên: 12/08/2014, 20:20

... obtund pain of needle insertion including infiltration analgesia and EMLA patch. Local anesthetics themselves may pro- duce pain on injection and many anesthetists are un- sure that infiltration ... pilot study of 20 patients having spinal an- esthesia by 25-guage Quincke needle without intro- ducer and any local infiltration, 90% of them had moderate to severe pain using NRS...

Ngày tải lên: 25/10/2012, 11:15

... protamine Hagedorn insulin measurement s of 40 IU in the morning and 15 IU in the e vening, and glycosylated hemoglobin levels >8%, which required adjustments of his insulin dose and addition of ... microvasculo- pathy ( neuropathy and diabetic skin microangiopathy), and an increased propensity for infection [3]. Endothelin may underlie the development of vascular c...

Ngày tải lên: 11/08/2014, 00:23