... toluidine blue stained sections was confirmed by FTIRM. Information on pro- teoglycan distribution in the explants was generated by creat- ing a chemical map made by integrating the area under the peaks ... surface of the explant (Fig. 2b, c). Chondrocytes developed changes resembling hypertrophy and there was a measurable increase in the proportion of empty chondrons. Notably...
Ngày tải lên: 09/08/2014, 06:23
... via bystander suppression. Immunotherapy using agents that induce T-cell-mediated bystander suppression makes it unnecessary to identify the self-antigens involved in the initiation of the arthritis ... prior to AA induction reduced the arthritic symptoms. In contrast, administration of the MMP-10 peptide after AA induction aggravated the arthritic symptoms. The present stud...
Ngày tải lên: 09/08/2014, 03:24
Báo cáo y học: "α Paradoxical effects of tumour necrosis factor-α in adjuvant-induced arthritis" pptx
... expression of p40, the common subunit of IL-12 and IL-23, in human and mouse myeloid cells, respectively [11,12]. In summary, this paper raises intriguing questions about the diverse roles played by ... CC: TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. Nat Med 1998, 4:78-83. 6. Kassiotis G, Kollias G: Uncoupling the proinflammatory from the imm...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo Y học: Identification of mammalian-type transglutaminase in Physarum polycephalum Evidence from the cDNA sequence and involvement of GTP in the regulation of transamidating activity potx
... region of the sequence is significantly conserved. The sequences around the GTP- binding region, catalytic site, and Ca 2+ -binding region are highly homologous to the corresponding regions of the human ... similarity was found in PpTGase with respect to the region for hydrolytic activity, no region homologous with the PLC-interacting region has been found. Whether the hydrol...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: " Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy" potx
... considered and overt clinical dehydration should be treated aggressively. 4) Consider increasing the frequency of serum chemistry evaluation during high dose treatment Increasing the frequency ... subcutaneously once daily) can result in proximal renal tubular dysfunction, a Fanconi-like syndrome characterized by glucosuria, aminoaciduria, hypophosphatemia, and bone pathology. In...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Long term follow up after surgery in congenitally corrected transposition of the great arteries with a right ventricle in the systemic circulation" pot
... information on coronary anatomy was explicitly available. In one patient a cir- cumflex coronary artery arose from the right coronary artery. In two patients a single coronary orifice was described. In ... years, range 2 - 17 years) in the Rastelli group. The mean follow- up period was 11.5 years (sd 9.8 years, range 7 days - 32.0 years). Coronary anatomy In 13 out of the...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: " Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats" potx
... stepping down to the metal rods, the latency is recorded as 2 min. Following the latency of staying on safe board, th e duration of stepping down till the animal again stayed on the board for 2 min ... falling down was recorded as the day one trial. On the follow- ing day P22, rats were placed on the rod again with the rolling rate of 5 rpm. The duration of holdi...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"
... history can be obtained by asking the indi- vidual “how many times do you laugh during your regular day?” and have the individual rate their level on a scale of one to ten. Furthermore, other ... hepatobiliary system, genitourinary system, reproductive system, CNS and psychiatric conditions, and then to specify the name of that con- dition. If the participant failed to indicate...
Ngày tải lên: 26/10/2012, 09:57
Tài liệu Báo cáo Y học: Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils pot
... & Snyder, F. (1973) The enzymic incorporation of arachidonic acid into ether-containing choline and ethanolamine phosphoglycerides by deacylation-acylation reactions. Biochim. Biophys. Acta ... ether-linked phospho- lipid subclasses accompanied the incorporation of this AA into 1-acyl-linked phospholipid subclasses (mainly in PtdCho/PtdIns). Conversely, the increase in the SA...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot
... could be inhibited by the increased availability of BAFF, which by binding to the BAFF- R induces upregulation of anti-apoptotic proteins [4,34]. Another concern is the association of increased ... bind proteoglycans [5]. With the above receptors expressed mainly on B cells, these cells are the major consumers of these cytokines. BAFF is produced constitutively by stromal cells wi...
Ngày tải lên: 09/08/2014, 08:23