Báo cáo y học: " Population specificity of the DNAI1 gene mutation spectrum in primary ciliary dyskinesia (PCD)" pdf

... Mutations in the DNAI1 gene , encoding a component of outer dynein arms of the ciliary apparatus, are the second most important genetic cause of primary ciliary dyskinesia (PCD), the genetically heterogeneous recessive ... Population specificity of the DNAI1 gene mutation spectrum in primary ciliary dyskinesia (PCD). Respiratory Research 201...

Ngày tải lên: 12/08/2014, 13:22

... amounts of sialylated Hex3 glycoforms were indicated. b Minor amounts of Hex2 and Hex3 glycoforms lacking acetyl groups or containing a second glycyl group were indicated. c Very minor amounts of ... 25. Methylation analysis of dephosphory- lated O S-1 showed significantly increasing amounts of terminal Glc and 2-substituted Hep, thereby indicating phosphorylation of these residues...

Ngày tải lên: 31/03/2014, 21:21

... quantity of cDNA of the gene of interest was directly related to the fluores- cence detection of FAM after 40 cycles. The amount of cDNA was calculated using a comparative C T method and the standard ... methods, the estimated amount of the gene of interest was normal- ized by the amount of glyceraldehyde-3-phosphate dehy- drogenase to compensate for variatio...

Ngày tải lên: 09/08/2014, 03:24

... TGF-β-signal-transducing smads to the membrane in the close vicinity of the receptor [19] (Figure 1). This interesting finding provides detailed anal- ysis of individual components of the TGF-β pathway and parallels ... HJT and TW participated in the coordination of the study, and RWK contributed to the design of the study and participated in the layout, writ...

Ngày tải lên: 09/08/2014, 10:20

... was performed in a nonblinded fashion. However, the results of the two double-blind studies are comparable with the results of the nonblinded studies in respect to the reduction of the incidence of VAP ... patients. They are necessary to enable monitoring of the efficacy of SDD and the detection of exogenous infection problems in the ICU. Furthermore, eve...

Ngày tải lên: 12/08/2014, 19:22

... four bases), they likely are part of the primary transcripts con- taining the miRNA cluster. To determine whether the retroviral integrations in this region affected the expression of the mir-106a ... mouse T lymphocyte tumor screen we found a high density of integrations upstream of the mir-106a microRNA cistron. In tumors containing an integration, the primary...

Ngày tải lên: 13/08/2014, 09:20

... polymorphisms would be important in influ- encing severity to the development of sepsis and MODS in trauma patients by changing the balance of pro-inflammatory and anti-inflammatory cytokines. There ... Lianyang Zhang 2 , Dingyuan Du 3 , Ping Hu 3 , Qing Liu 1 , Suna Huang 1 and Jianxin Jiang 1 1 State Key Laboratory of Trauma, Burns and Combined Injury, Research Institute of...

Ngày tải lên: 13/08/2014, 20:21

... over- crowding. The high frequency of mention of these dis- eases were directly associated with the high prevalence ofthesediseasesinthearea.Thisgoesontoexplain why many of the medicinal plant species ... generation gap caused by the over 20 years of insurgency in the area has brought about knowledge gap on the usage of medicinal plant species between the young and...

Ngày tải lên: 10/08/2014, 09:21

... yin-yang of PR-domain family genes in tumorigenesis. Histol Histopathol 2000; 15: 109-17. 3. Buyse IM, Takahashi EI, Huang S. Physical mapping of the retinoblastoma interacting zinc finger gene ... Shao G, Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated g...

Ngày tải lên: 25/10/2012, 11:15

... Biochemistry parameters In the present study, the amylase levels in the serum and urine were increased in the first 3 days and the first 5 days after HIFU ablation, respectively. But no significant ... clearly delineated from the surrounding normal tissues. Infiltration of inflam- matory cells and phorocytosis on the boundary were found in group C. Blood and urine...

Ngày tải lên: 25/10/2012, 11:18