Báo cáo y học: "Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus" pot

... is properly cited. Research article Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus Ying J Nie 1 , Mo Y Mok 1 , Godfrey CF Chan 2 , ... BMDCs, bone marrow-derived dendritic cells; BMCs, bone marrow cells; FLDCs, dendritic cells induced by FL; mDCs, myeloid dendritic cells; FL, FMS-like ty...

Ngày tải lên: 12/08/2014, 12:20

... 2c–e). In the former, CCR7 expression was detected mostly in the perivascular lymphocytic infiltrates of the sublining layer (Fig. 2b,o) and, only occasionally, in scattered cells in the sublining ... at the level of lymphocyte aggre- gates (Fig. 2e,f). Conversely, CCR5-positive cells were detected mainly in the lining layer and in the sublining zone of the superficia...

Ngày tải lên: 09/08/2014, 06:22

... A: Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus erythemato- sus patients. Stem Cells ... Chemokine and chemokine receptor analysis reveals elevated interferon-inducible pro- tein-10 (IP)-10/CXCL10 levels and increased number of CCR5+ and CXCR3+ CD4 T cells...

Ngày tải lên: 09/08/2014, 14:22

... are depleted of PyPu dinucleotides immediately upstream of the dominant TSS [-1,+1] (namely, [-2,-1] and [-3,-2]; fraction of PyPu dinucleotides shown as grey bars) and have a PyPu consensus ... spacing influences initiation site usageFigure 4 TATA-TSS spacing influences initiation site usage. Histogram showing the distribution of the four possible dinucleotides (PyPu, PyPy, Pu...

Ngày tải lên: 14/08/2014, 17:22

... trypsin, untreated AFP (UT AFP), and deglycosylated AFP (DG) are id entified. Bands smaller than 1 4 kDa in lan es containing trypsin were shown to b e trypsin autolysis products (trypsin-only ... [19]. Dimerization of smelt AFP is unlikely to increase activity by increased ice binding because only a dimer with perfectly aligned ice-binding sites would have enhanced binding to ice and...

Ngày tải lên: 24/03/2014, 03:21

... of cytokines in activation and function of γδ γδγδ γδ T cells activated indirectly through cytokines secreted by ab T cells, accessory cells and antigen presenting cells (APC). Cytokines were ... removal of γδ T cells early in cultures leads to greater proliferation of CD4 + cells and facilitates cloning Phenotypic and functional analysis of bovine γδ...

Ngày tải lên: 07/08/2014, 14:22

... certain inflammatory cytokines (IL-6, IL-1β) and by certain growth factors. Extracellularly, TIMPs inhibit MMP activity by forming high- affinity noncovalent complexes with MMPs. The amino-termi- nal ... amino-termi- nal domain of TIMP binds the active site of MMPs, inhibiting their proteolytic activity. The carboxy-terminal domain of cer- tain TIMPs has also the ability to form compl...

Ngày tải lên: 09/08/2014, 06:23

... orders of magnitude to fit into the space available [1,2], and the mechanism of chromo- somal packing in bacteria and the proteins involved is a long-standing question. In a recent study published ... analyzed and understood together. Nucleoid topology is strongly related to the binding patterns of NAPs. All the major NAPs, with the exception of Dps (the DNA-binding pro...

Ngày tải lên: 09/08/2014, 20:21

... positive ly correlates with the increasing concentration of DHPC. Protein-lipid interactions and Protein-LDLR binding of ApoE-(72-166) Proteins To identify and compare the lipid binding ability of the three ... three isoforms were significantly dissociated in the presence of dihexanoylphosphatidylcholine. Dimyristoylphosphatidylcholine turbidity clearance assay showed that apoE4...

Ngày tải lên: 10/08/2014, 05:21

... splicing machinery very efficiently by using the Rev protein which binds with high affinity and specificity to highly structured cis-acting RNA element present within the coding region of HIV-1 ... etic diversity and has been classified into various subtypes and recomb inant forms. While subtype B predominates in US and UK, it is sub - type C that is predominant in India, China...

Ngày tải lên: 10/08/2014, 05:21