Báo cáo y học: "he enigma that is the nucleus pulposus cell: the search goes on" pptx
Báo cáo y học: "he enigma that is the nucleus pulposus cell: the search goes on" pptx
... function. © 2010 BioMed Central Ltd The enigma that is the nucleus pulposus cell: the search goes on W Mark Erwin See related research by Gilson et al., http://arthritis-research.com/content/12/1/R24 EDITORIAL *Correspondence: ... previously thought? The paper by Gilson and colleagues that is the subject of the present editorial presents compelling data concern...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... activity. Another important feature conserved in this group of peptides is the cen tral Lys-Lys pair and the b asic nature of the peptides. It appears that the length of the peptide and this pair ... atural lesueurin by e lectrospray mass spectrometry, and HPLC. Bioactivity assays Antimicrobial testing. Synthetic lesueurin was t ested for antibiotic activity by the M icrobiolo...
Ngày tải lên: 31/03/2014, 15:20
Tài liệu Báo cáo Y học: Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity pot
... the notion that antizyme may be degraded together with ODC, they suggest that interaction with ODC is not essential f or the degradation of antizyme. This conclusion is supported mainly by the experiment ... of antizyme is also mediated by the proteasome as specific inhibitors of this protease effectively inhibit this proteolytic process. This result refutes the long-standi...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... is consistent with previous report that the stability of Ku-70 is compromised by the absence of Ku-80 [57]. This is the first report to show that Ku-80 expression is suppressed effectively through ... visualized by silver staining (unpublished data). In contrast, only the 70 kDa subunit was observed by South-Western blot analysis (Fig. 3A). This is consistent with previou...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: "he Association Among Lipoprotein-associated Phospholipase A2 Levels, Total Antioxidant Capacity and Arousal in Male Patients with OSA"
... Konya/ Turkey. 2. Department of Cardiology, Meram Medical Faculty, Selcuk University, Konya, Turkey. 3. Department of Biochemistry, Meram Medical Faculty, Selcuk University, Konya, Turkey. 4. Department ... This is the major negative result of the study. A possible explanation of this negative result that sensitivity of hs-CRP may be decrease due to the lower conventional risk...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: " A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hypertension among Japanese Females"
... However, this finding does not necessarily imply that there is a relationship between the NPPB gene and EH. Further studies of other polymorphisms are needed to determine whether there is an association ... Thus, it is possible that the plasma BNP level is not an accurate reflection of the function of the NPPB gene. In the present study, the overall distribution...
Ngày tải lên: 26/10/2012, 10:04
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... 5-methyltetrahydrofolate as a carbon donor [6] . This donor is synthesized by the methylenetetrahydrofolate reductase (MTHFR) gene from 5,10-methylene-tetrahydrofolate [9,10]. Reduction in the ... homozygous genotype. Only one band is seen at the approximately the 175 Bp. Figure 2. Plasma homocysteine in the studied groups. Bar Chart illustrating the plasma homocysteine...
Ngày tải lên: 03/11/2012, 09:49
Báo cáo Y học: DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells ppt
... apoptosis and necrosis. However, it is not known whether the k inase activity is involved in apoptosis. In the present study, we employed PC12 cells, extensively used as a model to study mechanisms regulating ... apoptosis. These ®ndings demonstrate that DAP kinase is an important component of the apoptotic machinery involved in ceramide- induced apoptosis, and that the intr...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides doc
... fashion by GTP and the hydro- lysis-resistant analogue GTPcS [26]. These data suggest that allosteric inhibition of GC-C by 2-substituted nucleotides is mediated by a region in the catalytic domain ... Mg 2+ serves as the cation cofactor, ATP potentiates ligand activation of pGCs presumably by binding to the KHD. The working hypothesis suggests that the KHD is intrinsicall...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3) pdf
... [15]. RESULTS P70 ik3-1 is phosphorylated by cyclin A/cdk2, cyclin E/cdk2, cyclin A/cdk3 or cyclin E/cdk3 which is produced in the baculoviral system We initially tested a hypothesis that p70 ik3-1 might ... strongly supporting that Ser274 is phosphorylated by cyclin/cdk3. Ser274 of ik3-1 also is phosphorylated by cdk3 in vivo Next, we asked whether Ser274 of p70 ik3-1 is phos...
Ngày tải lên: 24/03/2014, 04:21