... [5].ConclusionOur study provides an initial systematic evaluation of health-related quality of life in a large population of patients with pulmonary arterial hypertension. We foundprofound impairment in ... S, Nagaya N, Satoh T, Kyotani S, Sakamaki F, Fujita M,Nakanishi N, Miyatake K: Clinical correlates and prognostic sig-nificance of six-minute walk test in patients with primarypulmonary hypertension. ... in applica-tion to other populations and have not been validated for use in patients with cor pulmonale. Indeed, pulmonaryarterial hypertension represents a hybrid of respiratoryand cardiac...