Báo cáo y học: "B-lymphocyte stimulator/a proliferation-indu

Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf

... of 14 RESEARC H ARTIC L E Open Access B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by ... shown). The inhibition of BLyS, APRIL, and the heterotrimers by atacicept is consistent with the observed effects of atacicept and/ or mur...

Ngày tải lên : 12/08/2014, 12:20

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Báo cáo y học: "Pro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis" ppt

... necrosis [4]. Pooling of the data from these 183 patients by Bosscha and colleagues in a meta-analysis resulted in a group of 95 patients treated with prophylactic antibiotics and 88 patients without [5]. These ... attractive as it may allow the use of prophylaxis without the risk of inducing superinfec- tions through the use of long-term broad-spectrum ant...

Ngày tải lên : 12/08/2014, 19:22

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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"

... purposes) of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... including carbamazepine, phenytoin, phenobarbital, and lamotrigine. The triad of hypersensi- tivity includes fever, rash and internal organ involvement with onset o...

Ngày tải lên : 25/10/2012, 10:51

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Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

... spoiled by inaccurate positioning of the interacting groups. The contact area of the distamycin amidinium end was investigated by evaluating the hydrogen positions and interaction energy terms for the ... AT-rich sequences [1], thereby preventing DNA and RNA synthesis by inhibition of the corresponding polymerase reaction. The crystal structure determination of...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx

... the presence of increasing concentrations of Ca 2+ calmodulin, the inhibition dropped by  50% in each case. In addition, these peptides also inhibit the activity of calcineurin, another enzyme that ... with Ca 2+ calmodulin, they should also inhibit the activity of calcineurin. The four model peptides lesueurin, citropin 1.1, frenatin 3 and caerin 1. 9, all inhibi...

Ngày tải lên : 31/03/2014, 15:20

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Báo cáo y học: "Familial Polycythemia Caused by a Novel Mutation in the Beta Globin Gene: Essential Role of P50 in Evaluation of Familial Polycythemi" potx

... nature of oxygen binding with heme, and in turn, can change the affinity of Hb for oxygen. The majority of mutations affecting oxygen affinity result in high affinity Hb variants which result in ... expectancy and do not require phlebotomy. The therapies used for polycythemia vera such as phlebotomy and chemotherapy should not be used in patients who have pol...

Ngày tải lên : 08/08/2014, 16:23

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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot

... by the age-associated increases in the staining of thymocytes and microenvironmental cells, including the multilocular fat-storing cells. These data suggest that chemokines may influence the ... thymocytes with advancing age lead to a novel con- ceptual point of view concerning the understanding of the process of thymic physiology in aging, where the increa...

Ngày tải lên : 08/08/2014, 18:20

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Báo cáo y học: "Brain choline concentrations may not be altered in euthymic bipolar disorder patients chronically treated with either lithium or sodium valproate" pps

... second part of the study was much better controlled in terms of the patients receiving valproate monotherapy, only including bipolar Type I patients, and in using an external choline solution ... studied only 4 patients, all of whom were on lithium [18]. Another study examined 19 euthymic inpatients and found increased choline/creatine ratios in basal ganglia, but only...

Ngày tải lên : 08/08/2014, 20:23

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Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot

... anti- α-fodrin antibodies are present in SjS sera and that the majority of these antibodies are of the IgG and IgA class, but that their frequency in SjS sera is not higher than that of the classic ... measured by ELISA (Table 1). The presence of anti-fodrin antibodies in four sera of patients with secondary SjS was confirmed by immunoblotting (fo...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat" pptx

... successfully treat an established disease with an antibody against kininogen without inducing side effects or toxicity in either the rat or the mouse model of the disease. Competing interests The ... significantly increased levels of both proteins. These observations are explained by the fact that mAb C11C1 inhib- its the activation of HK, thus blocking KKS act...

Ngày tải lên : 09/08/2014, 06:22

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