Báo cáo y học: "Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints " potx
Báo cáo y học: "Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc" pdf
... also of interest to comment on the question of potential
compensation between the two TSPs. There is no evidence to
date for compensation. Although we have not tested whether
upregulation of TSP1 ... ingrowth into the body of the disc did not
occur.
The results of the quantitative assessment of the vascular bed
in soft tissue along the disc margins that we...
Báo cáo y học: "Development of a health care utilisation data-based index for rheumatoid arthritis severity: a preliminary study" ppt
... its
validity in other populations.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
GT analysed the data and drafted the manuscript. SS provided
support ... and
progress notes. A review of the VA electronic medical records
of the study population was conducted to obtain information
on individual components of the RA...
Báo cáo y học: "Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints." potx
... Development of proteoglycan-induced
arthritis depends on T cell-supported autoantibody production, but
does not involve significant influx of T cells into the joints. Arthritis
Research & Therapy ... and those treated with FTY720 (Figure 4d) in
the long-term experiments.
FTY720 treatment does not have an effect on the
occupancy of lym...
Báo cáo Y học: Development of a selective photoactivatable antagonist for corticotropin-releasing factor receptor, type 2 (CRF2) potx
... experiments using a
photoaffinity labeling technique is that the photoactivata-
ble ligand binds with high affinity to the receptor and that
the receptor is not destroyed or deactivated by the light
used ... significant differences between the relative agonist activities of the peptides:
j
, P > 0.001 vs.
control without peptide.
k
The ratio of cAMP production of transfec...
Báo cáo y học: "Efficacy of treatment with glycosaminoglycans on experimental collagen-induced arthritis in rats" pptx
... radicals. Treatment with the two GAGs pro-
duced a significant attenuation of cartilage injury.
The production of oxygen free radicals that occurs with
the development of arthritis in the articular ... with HYA and C4S in a rat model of CIA.
The choice of these two compounds from other GAGs was
made on the basis of the evidence that they show the best
antioxi...
Báo cáo y học: "Susceptibility of rheumatoid arthritis synovial fibroblasts to FasLand TRAIL-induced apoptosis is cell cycle-dependent" ppsx
...
phase.
Conclusions Our data indicate that the susceptibility of RASFs
to FasL- and TRAIL-induced apoptosis depends on the cell
cycle. These results may explain some conflicting data on the
ability of ... hypothesised that the suscepti-
bility of RASFs to receptor-mediated apoptosis depends on
the proliferation status of these cells and, therefore, analysed
the...
Báo cáo y học: "α Impact of VIP and cAMP on the regulation of TNF-α and IL-10 production: implications for rheumatoid arthritis" pps
... and
suggests that IL-10 augmentation is specific not only to
cell type but also to the stimulus.
Comparing these data with those found in the mouse, the
augmentation of IL-10 and downregulation of TNF-α ... raised by increasing the activity of adenylate
cyclase or by decreasing the activity of phosphodi-
esterases. In the light of the observation that a physiologi-...
Báo cáo y học: "Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis" ppt
... investigated.
Materials and methods
Patients and controls
The study was approved by the Ethics Committee of the
Medical Faculty of the MLU Halle-Wittenberg. All patients
attended the study after ... later
years, the OR of 0.31 points to inversion into a significant
protective effect.
Our data contrast with those of other investigations
reporting the lack of associa...
Báo cáo y học: " Pathogenesis of rheumatoid arthritis: how early is early" pdf
... identical to very
early rheumatoid arthritis. Evaluation of the cytokine profile at the
earliest time points after onset of symptoms could identify novel
targets that prevent progression to chronic ... (Th2) factors
contribute to the resolution. In this context, the study by Raza
and colleagues raises questions about the role of T cells in
RA and other forms of inflamma...
Báo cáo y học: " Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden" docx
... year of treatment
initiation, DAS28, and disease duration prior to treatment initi-
ation did not predict the level of adherence to therapy.
Discussion
The results presented in this study demonstrate ... by the treating physician, and inter-observer
variation in the classification of the stop reason therefore
exists. The reason for the low percentages of termination
be...
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