Báo cáo y học: "Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis" pps

... Access Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis Anne Friesgaard Christensen 1* , Grith Lykke Sørensen 2 , ... four years indicate, that subnormal SP-D is primar- ily linked t o systemic inflammation. According to this, depressed systemic SP-D may contribute to p...

Ngày tải lên: 12/08/2014, 12:20

... enzymes may therefore play an important role in RA. Introduction Rheumatoid arthritis (RA) is a chronic inflammatory polyarthri- tis, characterised by a proliferation of synovial cells and infiltra- tion ... [Swiss-Prot:Q13491 ] 1,480.0 FYVE, RhoGEF and PH domain-containing protein 4 2.5 Organelle/membrane [Swiss-Prot:Q96M96 ] BMP, bone morphogenetic protein; FYVE, phenylalanine...

Ngày tải lên: 09/08/2014, 01:22

... recombinant proteins leading to a compromised mitochondrial integrity rather then to an intrinsic property of the proteins. T his could e xplain the lack of r egulation by free fatty acids and purine ... UCP3, and possibly also UCP2, in any host system (i.e. not on ly cellular but also in tissue systems and even in transgenic animals) should be inter- preted with care. In supp...

Ngày tải lên: 21/02/2014, 15:20

... 2933 different from previously isolated minisatellite binding proteins, MSBPs, in their molecular sizes and DNA binding properties [25–27]. In this study, isolation and character- ization of a ... strands of the insulin minisatellite adopt hairpins with intercalated cytosine+.cytosine pairs. J. Mol. Biol. 272, 369–382. Ó FEBS 2002 Single-stranded C-rich DNA binding protein, LRP130...

Ngày tải lên: 31/03/2014, 23:20

... potential N-glycosylation sites, a cysteine rich substrate-binding domain and a stretch of 200 amino acids at the carboxyl terminus containing the catalytic serine, aspartate and histidine in a non-classical ... state. FP-biotin binds irreversibly to serine but not cysteine, aspartate and metallo- proteinases and labelled proteins are then isolated using streptavidin-agarose beads [...

Ngày tải lên: 09/08/2014, 07:20

... from normal PBMCs treated with IFN-α2a for 72 hours was examined by (e) flow cytometry with intracellular staining or (f) Western blotting with β- actin as a protein loading control. The experiments ... A, McMahon M, Taylor M, Brahn E, Hahn BH, Tsao BP: Association of increased interferon-inducible gene expression with dis- ease activity and lupus nephritis in patients with...

Ngày tải lên: 09/08/2014, 10:23

... 16), PPS instillation (PPS- inst, n = 10), saline instillation (saline-inst, n = 10) and model (injury only, n = 10) groups. Administration of surfactant The nebuliser was driven by an oxygen line ... 30 minutes later they were divided into five groups: model (injury only), PPS aerosol (PPS- aer), saline aerosol (saline-aer), PPS instillation (PPS- inst), and saline instillation...

Ngày tải lên: 13/08/2014, 15:22

... al. Homocysteine syn- thesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women. ... infection to hyper- homocysteinemia. 5. Conclusion This study was the first study that analyzed as- sociation between H. pylori infection and hyperhomo- cysteinemia in normal subjec...

Ngày tải lên: 31/10/2012, 14:34

... patients with CAD has hyperhomocysteinemia [17] and low folate intake with ensuing low folate serum concentrations is the main cause of this disorder [18]. A dietary folate intake of 350 µg/day is ... atherosclerosis, lipid-lowering agents and non-traditional cardiovascular risk factors, with special interest in homocysteine. He is a founding member of the Spanish Ath...

Ngày tải lên: 02/11/2012, 11:12