Báo cáo y học: "Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvemen" doc
Báo cáo y học: "Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvemen" doc
... tissue-type plasminogen activator; TNF:
tumor necrosis factor; u-PA: urokinase-type plasminogen activator; u-PA
-/-
:
urokinase-type plasminogen activator gene deficient; u-PAR: urokinase-type
plasminogen ... 12:R37
http:/ /arthritis- research.com/content/12/2/R37
Page 12 of 13
RESEA R C H ARTIC L E Open Access
Urokinase-type plasminogen activator and
arthritis progressio...
Báo cáo y học: " Absence of xenotropic murine leukaemia virusrelated virus in UK patients with chronic fatigue syndrome" docx
... ecotropic Friend and Moloney MLV
(Table 2) by assaying for a reduction in virus infectivity
following incubation of virus-containing supernatant
Figure 1 Sensitivity of PCR screening for XMRV in PBMC ... University
Q125 + ++ ++ - ND
+ indicates neutralising activity; ++ indicates strong neutralising activity; - indicates no neutralising activity; ND is no determined.
Groom et al. Retrov...
Báo cáo Y học: Domain organization, folding and stability of bacteriophage T4 fibritin, a segmented coiled-coil protein docx
... enthalpy of the transition f or the
E, SM4, SM1 and B1 fibritins increases linearly with an
increasing number of amino-acid r esidues in the coiled-coil
region. In contrast to the independent melting ... of
melting between the C-terminal domain and the coiled-coil
region (Fig. 3A). Significant stabilization of fibritin M, in
comparison with a wild-type fibritin, can be explained
mai...
Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... expression
increased in the aging thymus. The CCR5 ligands,
CCL4 and CCL5, increase in the thymic parenchyma
as revealed by the age-associated increases in the
staining of thymocytes and microenvironmental ... the thymus with age. Hy-
pothesizing that the increased expression of chemokines and the CCR5 receptor may play a
role in adipocyte recruitment and/ or differenti...
Báo cáo y học: "Extracellular mitochondrial DNA and oxidatively damaged DNA in synovial fluid of patients with rheumatoid arthritis" potx
... immunos-
timulatory mtDNA was involved in human arthritis by assay-
ing the levels of extracellular mtDNA in plasma and synovial
fluid (SF) samples from patients with rheumatoid arthritis
(RA) and from ... bands were revealed by
silver staining. The gels were scanned and the intensity of
each band on the gel was analyzed with IPLab Gel soft-
ware (BioSystematica, Plymouth, U...
Báo cáo y học: "Review Ageing, autoimmunity and arthritis" pps
... alterations resem-
bling those found in autoimmune diseases, especially in
RA and in systemic lupus erythematosus (SLE) [19], exist
in healthy aged individuals, including an increase in
autoantibodies, ... of arthritis, but in ageing and in auto-
immune diseases there is a complete disequilibrium
between proinflammatory cytokines and anti-inflammatory
cytokines [2,6,9...
Báo cáo y học: "Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development" docx
... clinical trials are
positive? The answer is this is ‘yes and no’. Certainly,
skepticism and vigilance are required with industry-
sponsored trials because there are inevitably large financial
interests, ... of
rheumatoid arthritis with methotrexate and hydroxychloro-
quine, methotrexate and sulfasalazine, or a combination of
the three medications: results of a two-year, randomiz...
Báo cáo y học: "Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study" pptx
... artery specimens with active
inflammation [6]. Thus, the process of aneurysm formation in
systemic inflammatory diseases is complex, multifactorial, and
likely involves immune and proteolytic ... from hypertension, heritable disorders
like Marfan syndrome, bicuspid valve disease, and inflamma-
tory and infectious processes. Among the systemic inflamma-
tory diseases, thora...
Báo cáo y học: "Hypoxia upregulates angiogenesis and synovial cell migration in rheumatoid arthritis" docx
... primarily affects the synovial lining, resulting in destructive
changes to the joints and soft tissues, most commonly in the
hand and wrist. Approximately 50% of patients with RA have
tendon involvement, ... Galardy RE, Grobelny D, Foellmer HG, Fernandez LA: Inhibition
of angiogenesis by the matrix metalloprotease inhibitor N-
[2R-2-(hydroxamidocarbonymethyl)-4-methylpentanoyl)]-
L-...
Báo cáo y học: "Toll-like receptors and NOD-like receptors in rheumatic diseases" pdf
... efficiently degrade cytosolic DNA [54].
Ankylosing spondylitis, TLR2 and TLR4
Ankylosing spondylitis is a multifactorial and polygenic
inflammatory rheumatic disease with a poorly understood
pathophysiology. ... Joosten and colleagues have shown a proinflammatory
role for NOD2 and an anti-inflammatory role for NOD1 in a
streptococcal cell wall induced model of arthritis [3...