Báo cáo y học: " Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursor" doc

... pre-osteoclasts to the receptor activator of NF-κB ligand signal. (a) CD14 + cells' representative m-RNA expression of receptor activator of NF-κB (RANK) and c-fms receptor from one donor. ... microscope (Nikon, Melville, NY, USA). Resorption assay Functional evidence of osteoclast formation was deter- mined by a lacunar resorption assay system using cell cul- tu...

Ngày tải lên: 12/08/2014, 11:23

... Key LL: Characterization of inter- feron gamma receptors on osteoclasts: effect of interferon gamma on osteoclastic superoxide generation. J Cell Biochem 2002, 84:645-654. 48. Cappellen D, Luong-Nguyen ... inhibition of osteoclastogenesis, NO production, and upregulation of CD11b and RANK surface expression. Surprisingly, this resistance is not mediated by inhibition of the JAK-...

Ngày tải lên: 09/08/2014, 01:21

... inflammation of synovium surrounding the tendons of the hand is often the first presentation of RA, and indeed up to 50% of patients with tendon disease can show tenosynovial invasion into the ten- don ... likely to influence cell inva- sion, in the context of angiogenesis (via degradation of extra- cellular matrix) and/or in terms of invasion by synovium of underlying tissue...

Ngày tải lên: 09/08/2014, 14:20

... compared to non-smokers of two age groups. In addition, an upregulation of TLR2 after LPS stimulation was only observed on non-smokers AM. An increased TLR2 surface expression on human mono- cytes in ... demonstrates the ratio of isotype control to surface molecule fluorescence (figure 2b). Regulation of PRR expression on AM To study the regulation of PRR expression after liga...

Ngày tải lên: 12/08/2014, 18:21

... point mutations in the V regions of transcriptionally active rearranged immunoglobulin genes. These mutations accu- mulate steadily during expansion of B-lymphocyte clones in the dark zone of the ... Germany), which has a very low error rate. Secondary amplification used individual primers for each of the first framework regions of each V H family in conjunction with a J H primer mi...

Ngày tải lên: 09/08/2014, 01:21

... for citation purposes) 1%. None other risk factors as age, gender, type or dura- tion of HAART or history of AIDS-defining event were related with serconversion. We did not find any serious adverse ... Koblin B, Taylor P, Rubinstein P, Stevens C: Effect of duration of hepatitis B virus infection on the association between human immunodeficiency virus type-1 and hepatitis B viral rep...

Ngày tải lên: 10/08/2014, 05:20

... labo- ratory [16]. Considering studies previously carried out in Light-dark cycle synchronization of circadian rhythms in blind primatesFigure 1 Light-dark cycle synchronization of circadian rhythms ... by their lower activity and, consequently, decreased motor activity feedback to the circadian system, or by the partic- ipation of classical photoreceptors (rods and cones) in the gener...

Ngày tải lên: 10/08/2014, 09:20

... antigen Consent Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the ... Polymorphous low-grade adenocarcinoma of the tongue. J Laryngol Otol 1996, 110:700-703. 5. Kennedy KS, Healy KM, Taylor RE, Strom CG: Polymorphous low- grade adenocarcinoma of the tongue...

Ngày tải lên: 11/08/2014, 14:21

... no history of hepatitis B vaccination in any of the subjects. Thepresenceofbodyinscriptionslikescarification marks or t attoos were statistically significant routes of transmission of HBV (c 2 = ... isto ry of blood transfusion, hist ory of previous dental or surgical procedures and previous history of circumcision/use ofsharpswerenotstatisti- cally significant routes of trans...

Ngày tải lên: 11/08/2014, 21:21

... ed that the type of interaction may depend on th e chronol- ogy of contamination with the two viruses: HCV super- infection in previously HBV infected patients, co-infec- tion or HBV infection in HCV ... seroligically-silent hepatitis B may contribute to poor interferon response in patients with chronic hepatitis C by down-regulation of type-I interferon receptor gene expression in...

Ngày tải lên: 12/08/2014, 01:21