Báo cáo y học: " The effect of interleukin-13 (IL-13) and interferon-g (IFN-g) on expression of surfactant proteins in adult human alveolar type II cells in vitro" docx
Báo cáo y học: " The effect of interleukin-13 (IL-13) and interferon-g (IFN-g) on expression of surfactant proteins in adult human alveolar type II cells in vitro" docx
... article as: Ito and Mason: The effect of interleukin-13 (IL-13) and interferon-g (IFN-g) on expression of surfactant proteins in adult human alveolar type II cells in vi tro. Respiratory Research ... study is toinvestigate the IL-13 and IFN-g effect on the expression of the surfactant proteins using primary human adult ATII cells in monolayer culture in vitro.Theexperi-ments with human ATII ... (IL-13) and interferon-g (IFN-g) on expression of surfactant proteins in adult human alveolar type II cells in vitroYoko Ito*, Robert J MasonAbstractBackground: Surfactant proteins are produced...
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Báo cáo y học: " The Raf-1 inhibitor GW5074 and dexamethasone suppress sidestream smoke-induced airway hyperresponsiveness in mice" pptx
... dexamethasoneintraperitoneally every other day or GW5074 intraperitoneally every day for three weeks. The tone of the tracheal ring segments was recorded with a myograph system and concentration-response ... signaling may provide a new optionfor treatment of smoking-associated airway hyperrespon-siveness. Effect of dexamethasone (A and C) and GW5074 (B and D) on the concentration-contractile curves of ... dexamethasone wasadministrated intraperitoneally every other day and GW5074 was administrated intraperitoneally every dayfor three weeks. The same volume of saline was used as asham control. The...
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Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf
... while the substitution slightly in uenced the enzymatic reaction steps of aldosteronesynthesis from DOC, s uggesting only minor functionalrelevance of lysine 152 in human C YP11B2. In contrast ... [17–19,41,42]. These stuc turesare mainly located in the C-terminal regions of CYP11B1 and CYP11B2. So far, the role of distinct amino acids of the N-terminal regions of human C YP11B isozymes h as ... 11b-hydroxylase capacity of CYP11B2 mutants in relation to the wild -type enzyme, whenincubated with 11-deoxycortisol. The 11b-hydroxylation of 11-deoxycortisol catalysed by the mutated proteins is shown...
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Báo cáo y học: "The effect of high correlated colour temperature office lighting on employee wellbeing and work performance" ppt
... carefully controlled labora-tory type environments. There is currently little under-standing of the effect of lighting conditions outside sucha setting, such as in the workplace. The current studyaddresses ... majority of participants on the intervention floor (41 of the 46)wished to keep the new lights at the end of the interven-tion period. The specific wellbeing effects of the new light-ing found in ... acceptability of a new type of indoor lighting. They were informed that the light-ing would be changed on both floors and that they wouldbe required to complete online questionnaires during the 14...
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Báo cáo y học: "The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis" pptx
... these mechanisms may include(1) altering the immune response and reducing the risk of infection [5,32,33]; (2) avoiding the pro-inflammatory effect of hyperglycaemia which may contribute to post-operative ... mortality in ICU patients. The reason for the discrepancy may be due to one or more of the following reasons; 1) The NICE study only lookedat g lucose control in the post-operative pe riod. The ... capillary leak syndrome, platelet dysfunction and a higher risk of post-operative complications[34,35]; ( 3) The insulin administration may protect the heart in ischaemic conditions by increasing...
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Báo cáo y học: "The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro" pdf
... Airway responsiveness of rats in the asthmaticgroup increased in comparison to the control groupafter induction by MCh (Figure 1).Inflammatory cells in BAL fluid The number of inflammatory cells ... upon the binding of IP3. In asth-matic ASMC, the expression of Ip3r mRNA did notdiffer from that of control ASMC. In contrast, the expression of Ip3r mRNA decreased in asthmatic ASMCafter induction ... levels in ASMC. In asthma, inflammatory cells can re lease cytokines that in turn induce increased cal-cium concentration i n ASMC, airway smooth musclecontraction, and airway hyper-responsiveness....
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Báo cáo y học: "The effect of provider- and workflow-focused strategies for guideline implementation on provider acceptance" pptx
... clarify the CPGs, and identifying championswho can informally encourage providers to adopt CPGs. In principle, the two types of strategies are complemen-tary and the effective implementation of ... detailing, grand roundspresentations) or the work context (e.g., computer reminders, modifications to forms). This studyinvestigated the independent and joint effects of these two types of implementation ... BND was primarily responsible for studydesign, survey materials, obtaining funding support, datacollection, and contributed to the interpretation, drafting and revision of the manuscript.AcknowledgementsThis...
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Báo cáo y học: "The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro" potx
... Airway responsiveness of rats in the asthmaticgroup increased in comparison to the control groupafter induction by MCh (Figure 1).Inflammatory cells in BAL fluid The number of inflammatory cells ... In this experiment, we demonstratedtha t NK-1R antagonist WIN62577 had the effect of inhi-biting ASMC migration in vitro, indicating thatWIN62577 may contribute to the inhibition of airwayremodeling. ... weredefined within single cells, and the average fluorescenceintensity of each region of interest was measured.Real-time PCR analysisTo investigate the expression of genes involved in Ca2+storage...
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Báo cáo y học: "The effect of CpG-ODN on antigen presenting cells of the foal" ppt
... the combination of cell surface marker expres-sion, using the monoclonal antibodies available for the horse species, and the expression of cytokines upon stim-ulation may reveal preliminary ... addition, this investigationrevealed an age-dependent limitation in the expression of MHC class II molecule in the APCs of the newborn and young foal, although the expression of the co-stimulatorymolecule ... DCs, and the presence of GM-CSFis synergistic for the expression of MHC class II, CD86,CD40 and CD83 molecules, mixed lymphocyte reaction and the secretion of Th1 cytokines by T cells [20].In...
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Báo cáo y học: " The effect of maternal common mental disorders on infant undernutrition in Butajira, Ethiopia: The P-MaMiE study" pot
... never/antenatal only/incident postnatal/chronic). None of the findings showedstatistically significant effect of CMD on nutritional sta-tus of infants (result not shown). Use of the SRQ score asa continuous ... scales of measurement (binaryor continuous), the frequencies of exposure and out-comes investigated, the timing at which the effect of exposure on the outcome was evaluated, and the quality of ... adjusted and fully adjusted effect of antenatal and postnatal prevalent CMD on infant undernutrition at the age of six and twelve months in the P-MaMiE study (Continued)Medhin et al. BMC Psychiatry...
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