... differen-tiation in erythroid progenitors. Polycytemia vera is a clonalmyeloproliferative disorder, leading to hyperproliferation of erythroid, myeloid and megakaryocytic cells. Sixty percent of polycytemia ... J.O., Whang-Peng,J.&Haynes,B.F.(1984)Conversionofastemcellleukemiafrom a T-lymphoid to a myeloid phenotype induced by the ade-nosine deaminase inhibitor 2¢-deoxycoformycin. Proc. Natl Acad.Sci. ... regulatory elements of many erythroid genes [e.g.globins, band 3, EKLF, FOG, erythropoietin receptor(EpoR) and heme biosynthetic enzymes] [27,28].GATA-2, a member of the GATA family, is expressed...