Báo cáo y học: " The role of leptin in the respiratory system: an overview" pdf

... up-regulation of many genes in E. coli including ahpC, mdaB, nfnB, nfo, sodA, yggX and ygfZ.By analyzing minimal inhibition concentration and inhibition zones of plumbagin in various gene-disruption mutants, ygfZ ... plumbagin were then determined. The MIC of the parental strain was expectedly much higher than those of the ΔygfZ and ΔsodA mutants (Table 3). To ensure that t...

Ngày tải lên: 10/08/2014, 05:21

Ngày tải lên: 13/08/2014, 01:20

... Crippin JS, McCashland T, Terrault N, Sheiner P, Charlton MR. A pilot study of the tolerability and efficacy of antiviral therapy in hepatitis C virus-infected patients awaiting liver transplantation. ... transplant are more ill. The resulting poor synthetic function, presence of hepatic encephalopathy and hypersplenism limit the candidacy of patients for interferon-based...

Ngày tải lên: 31/10/2012, 17:11

... glutamine and thereby give additional information into its potential role in ligand binding. We also made the three analogous mutants of mouse PXR: I282Q, Q404H and Q404A. The wild-type and mutant ... of the human and mouse PXR ligand binding domains. By modeling the human PXR ligand binding domain we have identified and mutated two polar residues in the puta- tive ligand b...

Ngày tải lên: 08/03/2014, 16:20

... were found, in the second study, to be activated by the MRN complex only in the presence of DNA strand ends, resulting in the phosphorylation of downstream targets [42]. Furthermore, both Nbs1 and the ... contains a forkhead-associated (FHA) domain and a Brca1 COOH-terminus (BRCT) domain in its NH 2 -terminal region, as well as an Mre11-binding domain and an ATM-bind...

Ngày tải lên: 16/03/2014, 13:20

... less than a year, a small but significant difference in the survival was shown in the two groups of the study: 4 year survival of 3% in the surgery arm and 7% in the radiotherapy arm. A 5 year ... radiotherapy, has been typically accepted as the cornerstone of therapy in SCLC [1]. Initially surgery was the treatment of choice for all types of lung cancer but...

Ngày tải lên: 10/08/2014, 10:20

... that the oxidant/anti-oxidant imbalance is resolved with smoking cessation it further supports the role of antioxidant disturbances in the progression of COPD. The data however can not indicate the ... burden both directly as a result of smoking and indirectly by the release of ROS which may not be adequately counterbalanced by the pulmonary antioxidant systems, resu...

Ngày tải lên: 12/08/2014, 13:22

... role of low-dose aspirin use, if any, may be minor on the risk of incident gout. Our study confirmed an increased risk of gout among users of cyclosporine (an immunosuppressant drug indicated in ... density sampling. This was done by generating at random a date encompassed within the study period for each of the members of the study population. If the random date...

Ngày tải lên: 12/08/2014, 15:22

... of their condition until late in their ICU stay and some of them only after their discharge to the ward. However, during their ICU stay they continue to have an emotional life, in a mixture of ... for stress in our patients. This can be explained by the traditionally strong family ties in the Portuguese culture. Pain came in fourth place in the ranking of stresso...

Ngày tải lên: 12/08/2014, 20:21

... that the interaction is independent from RNA and that the complex cofraction- ates with the miRNA miR-17. By using a two-hybrid assay, they map the interaction to the C-terminal domain in TRBP, ... Surprisingly, many RNAi suppressors are also inhibitors of the interferon (IFN)-induced protein kinase R (PKR) but the potential overlap between the RNAi and the IFN pathways...

Ngày tải lên: 13/08/2014, 09:21