Báo cáo y học: " Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium" doc

... 7500. Localization of GAD67 Expression in Human Airway Epithelium To determine the airway epithelial localization of GAD67 expression, bronchial biopsies were obtained by flexible bronchoscopy from the large airway ... 11:150 http://respiratory-research.com/content/11/1/150 Page 14 of 15 The data demonstrate there is expression of genes for a complete GABAergi...

Ngày tải lên: 12/08/2014, 11:22

... normally express the gene of interest. The advantage of using the BAC as a cloning vector is that it can carry as much as 200 kb of genomic DNA - typically enough to include most, if not all, of the ... Centers [8,9]. In addition, for some of the most interesting expression patterns, the project is developing lines where the BAC containing the gene promoter eleme...

Ngày tải lên: 14/08/2014, 07:21

... closely related family members is an artifact of hybridization. Profile of microRNA expression in the developing mouse brainFigure 3 Profile of microRNA expression in the developing mouse brain. ... technology for profiling the expression of microRNAs and other small RNAs and apply this technology to the developing mamma- lian brain. Recently, Krichevsky et al. descr...

Ngày tải lên: 14/08/2014, 14:21

... clus- tering of these genes was then performed to identify gene expression patterns among the study samples. As in the JDM study, a striking increase in the expression of a group of genes previously ... microarray system (Mergen ExpressChip DNA Microarray System Human HO4) in a study of 10 SLE patients and 8 healthy controls. The Han study also detected an increase...

Ngày tải lên: 09/08/2014, 01:23

... translation parameter. In this system, we use the Gabor function as the mother wavelet. The equation is given by: where ω p is the center of frequency and λ is the frequency bandwidth. In the present study, ... differences in signal intensity suggest that a superficial collagen network may be maintained in cartilage of the lateral condyle but may deteriorate in...

Ngày tải lên: 09/08/2014, 10:23

... a PiT1-binding immunoadhesin generated by f using the aminoterminal residues of the GALV (SEATO strain) Env, comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, ... W hether, a lack of staining may come from an absence of receptor/transporter or an altered accessibility remains to be determined. In any case, lack of staining reflec...

Ngày tải lên: 10/08/2014, 05:21

... aware of the initial injury and at times, deeply penetrating splin- ters cannot be visualized. In these cases, unfortunately, the only indication of retained foreign material might be swelling, ... injuries typically have an injury track that leads to the splinter, facilitating detection and removal. Older injuries, however, may present in the context of infection, inflammat...

Ngày tải lên: 11/08/2014, 12:20

... applied in this study to determine the copy numbers of PHoV genomes. The assay was established to detect the newly described parvovirus PHoV and the human PARV4/ PARV5 using primers binding within ... Schönbuch which were nearly identical to the later sampling places in the hunting sea- son 2007/2008. In general, sampling, age determination of animals, storing and hand...

Ngày tải lên: 12/08/2014, 04:20

... have documented evidence for increased endogenous NO synthesis, suggest ing that overproduction of NO may be important in the pathogenesis of RA.  e in amed joint in RA is the predominant ... lysosomal lysosomal degradationdegradation ȗ ȗ P725 NO ATP ATP NO Cytokines (INFCytokines (INF ȖȖ, IL, IL 2) synthesis2) synthesis NO T cell NO Nagy et al. Arthritis Research & T...

Ngày tải lên: 12/08/2014, 14:22

... to increase the number of neurones and the neuropeptide content in the airways [15,16], and both NGF and BDNF may evoke airway hyperreactivity in the airways [12-14]. In this respect, it is interesting ... there is evidence for a broad reg- ulatory role for neurotrophins in the airways. In addition to cells of the immune system, neurones may also be tar- gets for...

Ngày tải lên: 12/08/2014, 16:20