Báo cáo y học: " DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1" doc

... Respiratory Research 2010, 11:145 http://respiratory-research.com/content/11/1/145 Page 7 of 8 RESEA R C H Open Access DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction ... increased airway wall thickness [1]. The increase of the airway smooth muscle cell (ASMC) mass in asthma results in thickening of the airway wall...

Ngày tải lên: 12/08/2014, 11:22

... method yields approximately 60% of type II cells (positive for the lamellar body protein ABCA3). Major contaminating cell types are macrophages and fibroblasts. The viability of type II cells ... regulation of SP-D in non-antigen- related inflammatory changes of the lung. Recently, Casey and colleagues proposed an anti-inflammatory role of SP- D in a mouse model of bleomycin -in...

Ngày tải lên: 12/08/2014, 16:20

... and 2 Department of Physiology, University of Manitoba, Winnipeg, MB, Canada ADP-ribosylation has been coupled to intracellular events associated with smooth muscle cell vasoreactivity, cytoskel- etal ... that mono-ADP-ribosylation and not poly(ADP-ribosyl)ation was necessary for the sti- mulation of DNA synthesis by mitogens. Mitogen treatment increased concomitantly the activity...

Ngày tải lên: 17/03/2014, 09:20

... Slit3 reduces the migratory activity of synovial cells from patients with RA, potentially by repulsion of the cells in analogy to the neuronal system [4,9]. Deregulation of the Robo3 receptor in ... in synovial fibroblasts in RA correlates with aggressiveness of the fibroblasts. Slit3 reduces the migratory activity of synovial cells from patients with RA, potentially by repulsion o...

Ngày tải lên: 12/08/2014, 12:20

... J: 3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture. Circ Res 1998, 83:490-500. 16. Kim DY, Ryu SY, Lim ... chronic airways diseases. Statins were initially developed to inhibit the activity of 3- hydroxy-3 -methylglutaryl-coenzyme A (HMG-CoA) reductase and are widely prescribed to reduce hyperlip...

Ngày tải lên: 12/08/2014, 14:20

... pathophysiology of FDEIA has yet to be determined, but gut permeability is one factor that may play an important role in the development of FDEIA. 7 An animal study by Yano and colleagues using lysozyme- sensitized ... history is significant for hypothyroidism. She does not have any known allergies to foods or medications, nor does she have any history of Chet G. Wong: School of Medic...

Ngày tải lên: 08/08/2014, 21:20

... assessment of pulmonary fibrosis on day 28 after bleomycin injection in ICR mice by the Ashcroft score (n = 8) (a). Comparison of hydroxyproline contents of lung tissues on day 28 after bleomycin ... the hydroxyproline content of the lung tissue (Figure 4b). Assay of proliferation of MLg2908 TGF-β significantly increased MLg2908 proliferation (Fig- ure 5a). The proliferation...

Ngày tải lên: 12/08/2014, 16:20

... housing for their stock (Nyarko, Senior Animal H usbandry Officer, MOFA, Ejur a - per- sonal communication). Respondents in a study by MOFA in 2008 considered that about 60% of livestock in the district ... insights gained from this study on the feed system. Conclusions This study has documented as many as 175 feeds that small ruminants eat, most of which fall into the category of crop...

Ngày tải lên: 10/08/2014, 09:21

... effect of IL-1β on 5-hydroxytryptamine (5-HT) induced bronchoconstriction was evaluated in an in-vitro model for assessment of long-term effects of inflammatory mediators on the airway smooth muscle. ... calcium tran- sients in airway smooth muscle cells. Am J Physiol 1995, 269:L234-40. 36. Banes A, Florian JA, Watts SW: Mechanisms of 5-hydroxytryp- tamine(2A) receptor ac...

Ngày tải lên: 12/08/2014, 15:20

... Horacek M, Vislocky I: A retrospective survey of fibrinolysis as an indicator of poor outcome after cardiopulmo- nary bypass and a possible early sign of systemic inflamma- tion syndrome. Eur J ... care unit. Key messages • Hyperfibrinolysis may play a role in inflammatory response (IR) after cardiopulmonary bypass (CPB). • Inhibition of fibrinolysis with tranexamic acid may attenu-...

Ngày tải lên: 13/08/2014, 08:21