Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx

... the original work is properly cited. Research article Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment Lisa ... disease during IFN /β treatment and circulating IFN inducers [2,3]. Type I IFN activity in SLE is associated with disease severity [...

Ngày tải lên: 12/08/2014, 11:22

... CC, Lin YL, Huang JL: Association between serum inflammatory cytokines and disease activity in juvenile idiopathic arthritis. Clin Rheumatol 2002, 21:52-56. 37. Maini RN, Feldman M: How does infliximab ... major proinflammatory cytokines in RA joints and stimulate IL-6 production by synovial fibroblasts [33- 37], whereas IL-6 is a major circulating cytokine in RA that induces the...

Ngày tải lên: 09/08/2014, 06:22

... susceptibility to rheumatoid arthritis. Arthritis Rheum 1987, 30:1205-1213. 2. Meyer JM, Han J, Singh R, Moxley G: Sex influences on the pen- etrance of HLA shared-epitope genotypes for rheumatoid arthritis. ... Lasbleiz S, Bardin T, Prum B, Cornélis F: Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 2...

Ngày tải lên: 09/08/2014, 08:22

... validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28. Arthritis Res Ther 2006, 8:R57. 18. Deyo RA, Cherkin DC, Ciol MA: Adapting a clinical comorbidity index ... review study period. The variables for rheuma- tology visits, inflammatory markers and other laboratory mark- ers yielded the highest correlation with the RARBIS. In our...

Ngày tải lên: 09/08/2014, 10:23

... quantification of total SIV DNA, SIV 2 LTR circles and SIV RNA in tissue were performed as previously described [3]. In situ hybridisation SIV gag in situ hybridization combined with immunohis- tochemistry ... HAART initiated very early during acute infection on HIV reservoirs remains poorly documented, particularly in tissue kno wn to actively replicate the virus. In this c...

Ngày tải lên: 13/08/2014, 01:20

... 0.14*** ActiGraph-min: time spent in moderate -to- vigorous physical activity (2 × minutes spent in vigorous activity + minutes spent in moderate-intensity activity, ActiGraph-count: raw counts in hours with any ... lifting activities. This raises the possibility that the accuracy of the IPAQ-C may be improved by separating physical activity into occupational and leisure t...

Ngày tải lên: 14/08/2014, 08:20

... series of gel-shift experiments in order to generate a hierarchy of Hfq binding efficiency to these different RNAs harboring internal or 3¢ terminal presumptive binding sites. Interestingly, Fig. ... stimulates ompA mRNA decay by interfering with ribosomes binding. Genes Dev 14, 1109–1118. 11 Moll I, Afonyushkin T, Vytvytska O, Kaberdin VR & Blasi U (2003) Coincident Hfq bindin...

Ngày tải lên: 19/02/2014, 16:20

... actin CArG- binding factor is indistinguishable from the c-fos serum response factor. Mol Cell Biol 1989, 9(2):515-522. 9. Miano JM: Serum response factor: toggling between disparate programs of ... participated in the coordination of the study and the writing of the manuscript. SH participated in bioinformatics analysis. JYW led the study and participated in the design of...

Ngày tải lên: 10/08/2014, 05:21

... University of Tokyo, Japan The Sp family is a family of transcription factors that bind to cis-elements in the promoter regions of various genes. Regulation of transcription by Sp proteins is based on ... the activity of p300 is dependent on gene dosage during early embryogenesis. Thus, it is possible that Sp3 might compete for binding to DNA with Sp1-like prot...

Ngày tải lên: 22/02/2014, 07:20

... promoter is independent of TATA-binding-protein -associated factors and initiator-binding proteins. Mol. Cell Biol. 17, 2973–2984. 32. Weis, L. & Reinberg, D. (1992) Transcription by RNA poly- merase ... necrosis factor a-activation of P EC-A cells. However, the magnitude of this change induced by in ammatory conditions could be insufficient to affect cell surface a1,3-galactosyl...

Ngày tải lên: 08/03/2014, 16:20