Báo cáo y học: " Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells" pot

... Prulière-Escabasse et al.: Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells. Respiratory Research 2010 ... 9 RESEARC H Open Access Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport...

Ngày tải lên: 12/08/2014, 11:22

... Farkas 1 and Joseph Belagyi 1 1 Central Research Laboratory and 2 Institute of Biophysics, School of Medicine, University of Pe ´ cs, Hungary Conventional and saturation transfer electron paramagnetic resonance ... Selective modification of Cys707 strongly affects MgATP hydrolysis, and the motor function of myosin heads in the in vitro motility assay is blocked [27,28]. The m...

Ngày tải lên: 24/03/2014, 03:21

... 5–30% of patients with SLE, and this frequency varies depending on the detection system, the selection criteria for study cohorts and the ethnicity of the SLE population under investigation [14-19]. ... putative bridging effect of dsDNA on the reactivity of SmD1-negative samples (amino acids 83–119). Increasing concentrations of dsDNA (recombinant plasmid) showed an inhibi...

Ngày tải lên: 09/08/2014, 10:20

... proteoglycan content of both the AF and the NP and the recovery of disc-height loss by 6 weeks [17]. One could speculate that the maintenance of disc height is determined by the structural integrity ... substantial contributions to the study design and to writing the manuscript. SS also acquired and interpreted the data. YA and KA performed data acquisition, statistical analys...

Ngày tải lên: 09/08/2014, 14:22

... inflammatory aspect and very limited granulation tissue covered by purulent, fetid exudates. (C and D) After three weeks of standard therapy, little improvement was observed, and after five months of conventional ... lack of response, risk of amputation, and gen- eral deterioration in this patient’s condition, bosentan was initiated on a c ompassionate use basis, with inform...

Ngày tải lên: 11/08/2014, 00:23

... T, Matsuzawa Y, Izumiya Y, Miyata K, Nakayama M, Kaikita K, Obata T, Takeya M, Ogawa H: Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid ... agonism or to antagonism of tonically active endocannabinoids, we analysed whether or not LPS induces the formation of 2 endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachido...

Ngày tải lên: 11/08/2014, 03:20

... Rietschel 5 and Tilo Kircher 6 Address: 1 Section of BrainImaging, Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany, 2 Department of Psychiatry and Psychotherapy, RWTH ... made substantial contributions to conception and design and was involved in the genetic analyses. TK conceived of the study, and participated in its design and BMC...

Ngày tải lên: 11/08/2014, 17:20

... Unclear Yes Yes Unclear Unclear Cook et al. [16], 1998 Yes Yes Yes Yes Yes Yes Low Thomason et al. [25], 1996 Yes Yes Yes Yes Yes Yes Low Prod’hom et al. [26], 1994 Yes Yes Yes Yes Yes Yes Low Pickworth ... addressed Selective outcome reporting Free of other bias Summary risk of bias Prakash et al. [22], 2008 Yes Yes Yes Yes Yes Yes Low Kantorova et al. [23], 2004 Yes Yes Yes Yes Yes Yes...

Ngày tải lên: 13/08/2014, 21:21

... down- regulation of phagocyte activity may be involved in the mechanism of action of anti-TNF-α therapy [9]. BSA = bovine serum albumin; C3Zy = C3-coated zymosan; FMLP = N-formyl-methionyl-leucyl-phenylalanine; ... capacity. On the other hand, the inhibitory activity of the mAb on CD69 membrane expression on neutrophils indicates that these cells are among the possible targets...

Ngày tải lên: 09/08/2014, 06:22

... investigated in one study and a beneficial role of PTX on prevention of kidney injury was observed [11]. Ourstudy,confirmsthiseffectofPTXbypreventing rise of sCr at 24 and 48 hours. This may be related ... flow and contribute to the attenuation of i ntersti- tial inflammation, down regulation of monocyte chemo- attractant protein-1 gene expression, reduction in the expressio...

Ngày tải lên: 10/08/2014, 09:23