Báo cáo y học: " The effect of the pro-inflammatory cytokine tumor necrosis factor-alpha on human joint capsule myofibroblasts" ppsx

... histopatho- logical changes only on day 14 and day 18 when STA-5326 was administered during the entire course of EAU, the possi- bility exists that STA-5326 may be merely delaying the onset of EAU rather than ... decreasing the overall severity of inflamma- tion. However, STA-5326 also decreased inflammation when administered only during the effector phase of EAU, after t...

Ngày tải lên: 09/08/2014, 13:22

... were anesthetized and spinal cord ischemia was induced by temporary occlusion of the descending thoracic aorta by a coronary artery balloon catheter, advanced through the femoral artery. The animals ... intra-aortically and proximally to the occluded segment, 15 min prior to the release of aorta occlusion by deflation of the balloon. When 30 min of aorta occlusion was comp...

Ngày tải lên: 10/08/2014, 10:20

... virion production and infectivity. Influence of SR proteins on virion production and infectivity This was examined by monitoring the levels of HIV-1 vir- ion production under conditions of increasing ... splicing pattern by SR proteins modify viral protein synthesis The profound modifications of the HIV-1 splicing pattern by overexpression of one of the SR proteins wer...

Ngày tải lên: 13/08/2014, 09:21

... detected in the lungs of the control mice (Fig. 2d). In the immunohis- Effect of genetic vaccination on lung histopathology in an animal model of allergyFigure 2 Effect of genetic vaccination on lung ... intranasally. Results: The vaccinated mice showed a significantly decreased synthesis of total and HDM-specific IgE compared with controls. Analysis of the cyto...

Ngày tải lên: 13/08/2014, 13:22

... with RSODN. Downregulation of NFATc1 by RNODN To clarify the mechanism underlying the inhibitory effect of RNODN on osteoclastogenesis, we examined the expression of the NFATc1 protein in bone marrow cells ... 5b,d). Inhibitory effects of intra-articular injection of RNODN on joint destruction and osteoclast activity in rats with CIA To evaluate the effect of...

Ngày tải lên: 09/08/2014, 08:22

... modulation of tumor cell proliferation [38,39]. The cytokines studied in this work were care- fully chosen to include cytokines of the Th1 repertoire (IL-2R and sTNFR-II), in addit ion to one of the ... Cairo University, Cairo, Egypt. 4 Biochemistry Department, Faculty of Science, Cairo University, Giza, Egypt. Authors’ contributions A-RNZ: conception and design of the stu...

Ngày tải lên: 13/08/2014, 13:20

... expression of inflammatory mediators and cytokines related to bone destructionmRNA expression of inflammatory mediators and cytokines related to bone destruction. (a) Expression of mRNA for cyclooxygenase-2 ... greatly reduces the local expression of both these cytokines in the joints of arthritic mice, which may account for the block in joint erosion induced in the CIA mo...

Ngày tải lên: 09/08/2014, 06:23

... observed. The positive clinical effects that HBO 2 has in the treatment of chronic inflammation may relate to its effects on secretion of IL-1, IL-6, and TNF-a. The effects of HBO 2 on prostaglandin, ... monitoring cytokines and inflam- matory mediators will help us to explore the effect of hyperoxygenation on psoriasis and to elucidate its mechanism of action. Abbre...

Ngày tải lên: 11/08/2014, 17:21

... Mattyasovszky et al, The effect of the pro-inflammatory cytokine tumor necrosis factor-alpha on human joint capsule myofibroblasts Arthritis Research & Therapy 2010, 12:R4 Mattyasovszky et al, ... provided the original work is properly cited. Research article The effect of the pro-inflammatory cytokine tumor necrosis factor-alpha on human...

Ngày tải lên: 12/08/2014, 11:22

... over the progression of cancer; and the second question is whether the PR domain alone possesses anticancer activity. In this study, we quan- titatively analyzed the mRNA expression level of ... transfection, respectively. The PR domain expression in the transfected HuH7 cells was confirmed by Western blot after 24 hr of transfection (C). Conclusion In this study, RIZ...

Ngày tải lên: 25/10/2012, 11:15