Báo cáo y học: " The role of the bronchial microvasculature in the airway remodelling in asthma and COPD" pps

... provided the knockout mice used in the study. PS and NW generated the recombinant TF. Figure 5 Role of fibrin in soluble tissue factor-induced inflammationRole of fibrin in soluble tissue factor-induced ... after injection. Fibrin formation and deposition was significantly diminished in PAR-4-deficient mice and underlines the important role of fibrin in infla...

Ngày tải lên: 09/08/2014, 10:23

... high and constant level of c-Myc. Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc by phosphorylation of the serine 62 residue in the N-terminal of c- Myc [24]. They ... hypothesized that c-Myc plays a central role in TGF1 signaling for cell growth stimulation. Additionally, to examine the possibility of involvement of the MAPK...

Ngày tải lên: 09/08/2014, 01:22

... reported on the role of cytokines in RP, either in patients or in the corresponding animal models. In the CIA model, several cytokines have been shown to play major roles in the inflammatory process, ... scores. However, the symp- toms in these strains did not proceed in relapses as they did in the QD and B10.Q mice, and therefore resulted in a lower mean...

Ngày tải lên: 09/08/2014, 01:24

... of YgfZ followed by Figure 2 Different roles played by YgfZ and SodA in counteracting plumbagin. The ΔygfZ and ΔsodA strains were transformed with pQE- sodA and pQE-ygfZ to express SodA and YgfZ, ... and the Δyg fZ strains and the parental strain were tested (Table 3). Therefore, adding a methyl group to the 3-position of naphtho quinone ring apparently diminishes t...

Ngày tải lên: 10/08/2014, 05:21

... by sub-acu te and chronic low back pain and/ or sciatica: this exerts an important impact on the quali ty of life, causing interfer- ence of sleep and enjoyment of life. Many clinical studies ... of Physical Medicine and Rehabilitation, University of Foggia, Foggia, Italy Full list of author information is available at the end of the article Ranieri et al. Journal...

Ngày tải lên: 10/08/2014, 10:20

... for the hypothesis that Cys341 is not only located at the S1 binding site [5–7,9], but the hydrophobicity of the thiol group also plays a role in substrate binding and interacting with the hydrophobic ... thiol group (Cys341) is involved in substrate binding at the S1 subsite and in maintaining the width and depth of the S1 subsite; (b) the rearrangement o...

Ngày tải lên: 08/03/2014, 23:20

... serine residues carrying O-linked glycan chains and distributed in tandemly repeated motifs in the central part of the protein backbone. Mucins are known to play important roles in the lubrication and protection ... single cell type may result in modulation of the properties of the molecule. On the other hand, the alternative RNA splice forms may only function...

Ngày tải lên: 17/03/2014, 23:20

... article by Terry Smith and William Cruikshank in the Journal of Immunology provides fascinating yet unexpected insights into how autoantibodies contribute to the maintenance of inflammatory disease ... chronic inflammation (both local and systemic), and alterations in the immune response, including changes in the T-cell repertoire and the production of autoantibo...

Ngày tải lên: 09/08/2014, 06:22

... kcal/day. On day 21 in hospital, a semi-solid enteral product of 400 kcal/267 g ( PG Soft™,Terumo,Tokyo,Japan)was administered for 15 minutes 3 times a day, which was then followed by 250 mL of semi-solidified ... or nose wings accompanying insertion of the nasogastric tube was observed. Compliance of the large-bore naso- gastri c tube was favorable, and he did not try to remo...

Ngày tải lên: 11/08/2014, 14:21