Báo cáo y học: " Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression" ppsx
... IL-1b,IL12p40andMIP-1b.Inaddi- tion to its antioxidant effects, quercetin may attenuate lung inflammation by inhibition of protein and lipid kinases involved in inflammatory cytokine and chemo- kine production. Quercetin ... and MMP1 2 and increases expression of SIRT1 in elastase/LPS-exposed mice. mRNA expression of Mmp9 , Mmp1 2, and Sirt1 was measured by qPCR. MMP...
Ngày tải lên: 12/08/2014, 11:22
... is becoming an increasingly common cause of disability [1,2] Diarthrodial joint damage assessment of the knee joint in par- ticular is crucial for monitoring OA disease progression and for eventually ... shown). Biomarkers Level of urinary C-terminal cross-linking telopeptide of colla- gen type II (U-CTX-II), a biological marker of collagen type II degradation, was measured b...
Ngày tải lên: 09/08/2014, 07:20
... accumulating evidence indicating that renal inflam- mation played a key role in the pathogenesis of DN. it was demonstrated that diabetes increased proinflamma- tory cytokines including TNF-a,IL-1b ... nephropathy by enhancing renal inflammation. Clin Exp Pharmacol Physiol 2010, 37(3):277-82. 39. Bondar’ IA, Klimontov VV, Nadeev AP: Urinary excretion of proinflammatory cytokines and t...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"
... [4]. Gout is a clinical syndrome caused by the deposition of monosodium urate monohydrate crystals into synovial, bursal, and cartilaginous tissue. The underlying metabolic disorder is hyperuricemia. ... Acute gouty arthritis refers to acute inflammation due to the pre- cipitation of urate crystals within a joint. Gouty attacks may be precipitated by trauma, starvation, surgery, inges...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "A severe coarctation of aorta in a 52-year-old male: a case report"
... Ascending aortography Figure 2 Descending aortography Discussion Aortic coarctation is a congenital vascular lesion typically diagnosed in early life, accounting for 5 to 10% of all ... fatigue and dyspnea in his fifth decade of life. Conflict of interest None declared. References 1. Grech V. Diagnostic and surgical trends, and epidemiology of coarctation of the...
Ngày tải lên: 25/10/2012, 11:40
Báo cáo y học: "Sustained High Quality of Life in a 5-Year Long Term Follow-up after Successful Ablation for Supra-Ventricular Tachycardia. Results from a large Retrospective Patient Cohort"
... symptoms like tachycardia, increasing incidence of episodes over time, reduction in physical work ca- pacity, dyspnea and angina pectoris. These symptoms were the main reasons why patients seeked ... im- provement. Main symptoms before ablation, such as tachycardia (91.5%), increased incidence of tachycardia episodes over time (78.1%), anxiety (55.5%) and reduced physical capacity i...
Ngày tải lên: 03/11/2012, 11:44
Báo cáo Y học: Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell line pptx
... cell-free proteasome system by protein kinase inhibitors We examined the involvement of TPH phosphorylation in proteasome-driven degradation of the enzyme in vitro.Our system contained extracts of RBL2H3 ... non-neural TPH, rat pineal enzyme was reported to increase in enzymic activity by treatment with cAMP [35]. The authors, Fig. 3. Insignificant incorporation of 32 P into...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo y học: "Long-term benefits of omalizumab in a patient with severe non-allergic asthma" ppt
... signifi- cantly i mprove asthma control and quality of life, with an excellent safety profile [3-5]. Actually, as set by the European Medicine Agency (EMA) [6] and GINA Guidelines [7], in Europe ... during the first months, showing a rise after four years. This could be explained by the bron- chial remodelling caused by t he long-standing ashtma, which needed several months of the...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... (dehydro- genation, hydroxylation, and N-dealkylation), mainly by cytochrome P450 2D6 (CYP2D6) and cytochrome P450 3A4 (CYP3A4) [60]. The parenteral drug is excreted only in traces. There is only ... (7-(4-[4-(2,3-dichlorophenyl)-1-piperazi- nyl]butyloxy)-3,4-dihydro-2 (1H)-quinolinone (OPC- 14597), is a derivative of the dopamine autoreceptor ago- nist 7-(3-[4-(2,3-dimethylphenyl)piper...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "A psychophysiological investigation of laterality in human emotion elicited by pleasant and unpleasant film clips" pptx
... reported by Hawk and Cook [23]. In a study of the laterality of emotion, they applied tactile probes (an air puff to the side of the face) in place of acoustic probes, using the slide-vi ewing paradigm. ... details 1 Department of Psychology, Faculty of Health and Social Sciences, University of Bedfordshire, Luton, UK. 2 Department of Psychology, Institute of Psychiatr...
Ngày tải lên: 09/08/2014, 01:21