Báo cáo y học: " Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle" doc
Báo cáo y học: " Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle" doc
... Recently, it has been shown that acetylcholine, by acting on
muscarinic receptors, is also involved in airway inflammation and remodelling. The mechanism(s) by which
muscarinic receptors regulate inflammatory ... synergistic effect of muscarinic
receptor stimulation with CSE
PKC plays an important role as a signalling intermedi-
ate in pro-inflammatory cytokine secretion b...
Báo cáo y học: " Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage" ppt
... sensitivity of
HIV-1 macrophages through the inhibition of the activity
of the pro-survival cytokine macrophage colony-stimu-
lating factor (M-CSF) [162]. Finally, several AKT inhibi-
tors including ... could syner-
gistically reactivate HIV-1 replication in latently
promonocytic cells by increasing the ratio of Sp1/Sp3
[100]. Serpin B2, a serine protease inhibitor induced in
acti...
Báo cáo Y học: Detailed characterization of polydnavirus immunoevasive proteins in an endoparasitoid wasp doc
... respectively, instead of the calyx
cells. Further, the expression of IEP proteins is not
synchronized with that of CkPDV capsid proteins; IEP
proteins were observed approximately one day after the
initiation ... (IEP-1) deter-
mined in the prior study [21] is underlined. The
amino acid sequence (10 amino acids) of IEP-2
determined in the present study is also
underlined. Potential...
Báo cáo y học: "The role of pleiotrophin and β-catenin in fetal lung development" doc
... W, Yamin M, Noda M, et al.:
Pleiotrophin signals increased tyrosine phosphorylation of beta beta-
catenin through inactivation of the intrinsic catalytic activity of the
receptor- type protein ... Perez-Pinera P, Deuel TF: Fyn is a
downstream target of the pleiotrophin /receptor protein tyrosine
phosphatase beta/zeta-signaling pathway: regulation of tyrosine
phosphorylation o...
Báo cáo y học: "The use of bispectral index monitors in paediatric intensive care'''' doc
... reasonable
sensitivity of 89.7% but a low specificity of 38.6%. That
study served to highlight the inadequacy of clinical scoring
systems in the assessment of sedation in those receiving
neuromuscular blocking ... monitoring sedation in critically ill children,
but that this role has yet to be clearly defined. It must be
remembered that the optimal range of BIS scores for vary...
Báo cáo y học: "Prognostic value of brain natriuretic peptide in acute pulmonary embolism" docx
... only by dyspnoae, but also by RV dysfunction leading to
BNP release. In hemodynamically stable patients, RV dysfunc-
tion as observed by echocardiography has been shown to be
able to identify ... PE.
Table 1
Characteristics of included studies
Reference Study
design
Patients,
number
Hemodynamic
instability
(number)
Timing of BNP
sampling
Thrombolysis,
number
Age, years Male,
percen...
Báo cáo y học: " Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma" doc
... air-
ways is increased activity of arginase, which hydrolyzes L-
arginine into L-ornithine and urea [10]. Arginase is
expressed in the airways [12] and has shown to be func-
tionally involved in ... Remarkably, inhibition of arginase
activity by the specific inhibitor N
ω
-hydroxy-nor-L-
arginine (nor-NOHA) completely reversed the airway
hyperreactivity to the level of unchallenge...
Báo cáo y học: "Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cell" pdf
... Hawrylowicz CM, O’Garra A:
In vitro generation of interleukin 10-producing regulatory
CD4
+
T cells is induced by immunosuppressive drugs and
inhibited by T helper type 1 (Th1)- and Th2-inducing
cytokines. ... activation
of naive T cells in vivo.
When ligands become receptors: the
induction of indoleamine 2,3-dioxygenase
(IDO) by T
reg
cells expressing CTLA-4
The linkage between reg...
Báo cáo y học: " Molecular mechanisms of autoimmunity triggered by microbial infection" potx
... revealed other
MyD88-independent signalling pathways involving the
Toll-IL-1 receptor (TIR) domain-containing adaptor molecules
TRIF (TIR domain-containing adaptor protein-inducing-
interferon beta) ... immunity
PAMPs that ligate TLRs induce potent mechanisms of innate
antimicrobial immunity. TLRs that signal through MyD88
induce NF-κB-dependent expression of pro-inflammatory
cytoki...
Báo cáo y học: " Genetic mechanisms of knee osteoarthritis: a population-based longitudinal study" pdf
... possible. The family
structure of each of the 163 offspring ranged through one off-
spring per family (n = 48), two offspring per family (35 families,
n = 70), three offspring per family (9 families, ... measures of physical activity included measurement
of muscle strength by dynamometry at the lower limb (involving
both legs simultaneously). The subject was instructed in each
techn...