Báo cáo y học: "Effective rheumatoid arthritis treatment requires comprehensive management strategies" docx

... Outcomes Study Short Form 36. Editorial Effective rheumatoid arthritis treatment requires comprehensive management strategies Chad S Boomershine Division of Rheumatology and Immunology, Vanderbilt ... disease activity. The ten- dency for DAS28 scores to overestimate RA disease activity in RA-FMS patients has been demonstrated previously [3]. FMS independently increases DAS28 score...

Ngày tải lên: 12/08/2014, 11:22

... early synovitis that develops into rheumatoid arthritis (RA); 2, early synovitis that develops into non -rheumatoid persistent synovitis; 3, early non-crystal-related resolving synovitis; 4, crystal-related ... early synovitis that develops into rheumatoid arthritis (RA); 2, early synovitis that develops into non -rheumatoid persistent synovitis; 3, early non-crystal-related resol...

Ngày tải lên: 09/08/2014, 06:22

... inhibitory factor production by rheumatoid arthritis synoviocytes and its regu- lation by Th2 cytokines. J Immunol 1998, 161:409-414. 44. Mott JD, Werb Z: Regulation of matrix biology by matrix ... with unclassified polyarthritis and early rheumatoid arthritis. Rela- tionship to disease activity, bone mineral density, and radio- graphic outcome. J Rheumatol 2004, 31:1698. 53. Maksymowy...

Ngày tải lên: 09/08/2014, 14:22

... potently and selectively by inhibiting wild-type forms of c- KIT. In vitro masitinib has shown greater affinity and selectivity for human and murine c-KIT receptor (wild-type: half inhibitory concentration ... c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis. Ann Rheum Dis 2005, 64:1126-11...

Ngày tải lên: 09/08/2014, 14:22

... article Identification of arthritis- related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis Noriyuki Fujikado, Shinobu Saijo and Yoichiro Iwakura Center ... replicates; poly (A) + RNA was purified on oligo (dT)- cellulose columns. RNA quality was confirmed by spectropho- tometry and electrophoresis on formaldehyde gels. Microarray analysis...

Ngày tải lên: 09/08/2014, 08:22

... dos- age used by Rothova et al was 250mg a day or 500mg every other day and therapy was associated with pyrimethamine 100mg on the first day that was fol- lowed by 50mg a day. Prophylaxy of recurrence ... trials. [2] A survey of the opinion of oph- thalmic specialists in uveitis was performed recently by Gary Holland. [3] The reasons that were commonly accepted to introduce a therapy wer...

Ngày tải lên: 03/11/2012, 11:01

... IL-10 levels are elevated in rheumatoid arthritis synovial fluid, these findings may have relevance to rheumatoid arthritis. Keywords: antibody, arthritis, autoimmunity, cytokines Open Access Although ... transcription in human monocytes. Blood 1997, 89:4461. 10. Ding L, Linsley PS, Huang LY, Germain RN, Shevach EM: IL-10 inhibits macrophage costimulatory activity by selectively inhi...

Ngày tải lên: 09/08/2014, 01:21

... indi- vidually, since different patients may have diverse and multiple symptoms with variable severity. Mild disease requires no or little therapy, usually nonsteroidal anti-inflammatory medica- tions ... pro-inflamma- tory cytokines. However, despite an extensive clinical history of use in rheumatoid arthritis and SLE [1], their mechanisms of anti-inflammatory action have not yet been...

Ngày tải lên: 09/08/2014, 07:20

... clinical onset of CIA as determined by the average arthritis score per effected paw began approximately on day 28. Initiation of arthritis was delayed by 7 days in the CII-pulsed LF-treated DC ... 10 days, and T lymphocytes from draining lymph nodes and spleens were isolated. Finally, a KLH-specific recall response was performed as described later. Mixed lymphocyte reaction At day 4 of .....

Ngày tải lên: 09/08/2014, 08:22

... inflammatory cytokines in RA patients by inducing anti-inflammatory cytokines or neutralizing pro-inflammatory cytokines should be critically evaluated before considering this form of therapy. Depletion ... autoim- mune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis. Ann Rheum Dis 2005, 64:599-605. 76. Miyazawa S, Nishida K, Komiyama T, Nakae Y, T...

Ngày tải lên: 09/08/2014, 08:23