Báo cáo y học: "α The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis" pot

... model. Editorial The role of anti- αα -actinin antibodies in the pathogenesis and monitoring of lupus nephritis Pierre Youinou 1 and Chaim Putterman 2,3 1 Laboratory of Immunology, Brest University Medical ... strongly to α-actinin [12,13]. Moreover, an increase in serum anti-α-actinin antibodies in lupus patients was associated with a 2.5-fold increase in...

Ngày tải lên: 12/08/2014, 11:22

... clinical and MRI findings. Clinical definition of arthritis mutilans Clinical digitised photographs of the hands and feet were obtained in 25 of the 28 patients. These were examined by a rheumatologist ... pertain only to baseline findings in these patients, before administration of the study drug or placebo. All patients gave informed consent according to the require-...

Ngày tải lên: 09/08/2014, 01:22

... conceived the study, participated in the design and co-ordination of the study, and participated in the interpreta- tion of the results. T Imado and SK performed the animal study and histologic analysis. ... markers of endothe- lial injury (thrombomodulin) and interstitial lung injury (KL-6), suggesting that elevation of serum HGF counteracts the endothelia...

Ngày tải lên: 09/08/2014, 08:22

... clinical and MRI findings. Clinical definition of arthritis mutilans Clinical digitised photographs of the hands and feet were obtained in 25 of the 28 patients. These were examined by a rheumatologist ... recruitment and participated in data entry. JL partici- pated in data entry and analysis. FMM conceived of the study and coordinated patient recruitment, data...

Ngày tải lên: 09/08/2014, 13:22

... sex of the patient, or the locati on, size or endoscopic appearances of the polyp. The most serious problem in PJS is an increased risk of cance r in the gastrointestinal tract. The occurrence of cancer ... of cancer in the gastrointestinal tract has been reported in 20-25% of patients with PJS, and a risk of cancer in other organs has been also reporte...

Ngày tải lên: 10/08/2014, 23:21

... [3,4]. The clinical course is non-specific and depends on the site of involvement, the size of the cyst, and the pressure caused b y the enlarged cyst [1]. Usually, it presents as an inert, painless, ... adjacent sites may be another mechanism of infection [6]. In our case, the hydatid cyst was located subcuta- neously. The patient had not undergone previou s sur...

Ngày tải lên: 10/08/2014, 23:21

... vein resulting in disruption of the endothelial-intercellular junctions and seepage of the drug into the interstitial space [1]. Extravasation of the highly albumin-bound (70- 90%) phenytoin increases the ... alleviate the vasospasm and the pain while preserving the motor function for the patient to perform active movements of the finger and hand. Introduc...

Ngày tải lên: 11/08/2014, 11:22

... it indicates the presence of peritoneal hemorrhage. The standard treatment for ectopic pregnancy is surgery by laparoscopy or laparotomy depending upon the condition of the patient. The main ... factors, and the detection of an intrauterine pregnancy does not exclude the possibility of the simultaneous existence of an ectopic pregnancy. Hence, in all patients of...

Ngày tải lên: 11/08/2014, 14:20

... actually not covered by these guidelines, and there are no other indications on the management of these patients in the literature. The estimated annual incidence of MI, new and recurrent in the ... considered the low age and the low cardio- vascular risk profile of the patient at the time of acute MI, the absence of symptoms after the event and the...

Ngày tải lên: 11/08/2014, 19:21

... details, reviewing the literature and drafting the manuscript. AC was involved in reviewing the literature and proofreading the manuscript. VA approved the final manuscript. Consent Written informed ... have no competing inter- ests. Authors' contributions EP is the senior author and was involved in collecting patient details, reviewing the literature and final...

Ngày tải lên: 11/08/2014, 23:21