Báo cáo y học: " Pharmacological characterisation of antiinflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation" ppt

... al.: Pharmacological characterisation of anti- inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation. Respiratory Research 2010 11:126. Submit your ... primary functions of preclini cal disease models is to assess the potential efficacy of candidate compounds, ideally one would examine the same endpoints in the mo...

Ngày tải lên: 12/08/2014, 11:22

... process, baking quality, taste and storability of the resulting injera. The farmers consider the injera from these land- races as tasty and filling, soft, fluffy, spongy with good and well distributed ... rain starts. Otherwise, early maturin g types ca n be planted as late as April and harvesting may go into July where there is a risk of damage by the main season rainfall. Belg b...

Ngày tải lên: 10/08/2014, 09:21

... are in a superior state of respiratory health and were better able to compensate upon expo- sure to methacholine (by incr easing RR, and PIF and maintain ing low Ti and Te) in order to maintain ... airways obstruction in inflammatory processes [25-28]. Finally we examined the peak inspiratory (PIF) and expiratory (PEF) flow rates which indicate the forcefulness of the insp...

Ngày tải lên: 12/08/2014, 11:23

... simultaneously in Pseudomonas aeruginosa-induced lung injury in rats [8], the oxygenation further deteriorated – beneficial effects could only be shown when rhAPC was given post injury in various ovine models ... origin. Low levels of protein C in acute lung injury are associated with poor clinical outcome. The present article discusses the beneficial effects of rhAPC in ole...

Ngày tải lên: 13/08/2014, 11:23

... data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. All authors partici- pated in the conception and design of the study; analysis and interpretation ... accordingly. This brings into question not only the quality of the survey methodology, but also the difficulties epidemiologists face in interpreting results a...

Ngày tải lên: 13/08/2014, 13:21

... signalling pathway in patients with sepsis. Shock 2008, Suppl 1:73-77. 5. Joyce DE, Grinnell BW: Recombinant human activated protein C attenuates the inflammatory response in endothelium and monocytes by ... vided the original work is properly cited. Pro and anti-inflammatory cytokine profiles To establish Th1/Th2 profiles, several cytokines were measured in serum at T1 and T2: IL...

Ngày tải lên: 13/08/2014, 21:21

... were obtained before the examination, and weight and height were measured in all subjects. The body mass index (BMI) was computed by dividing the body weight in kilograms by the square of the ... University School of Medicine, Tokyo, Japan. Genotype determination DNA was extracted from whole blood using the phenol/chloroform method. The VDR polymorphism was genotyped usin...

Ngày tải lên: 08/08/2014, 16:23

... 'sympathetically maintained pain' [5]. Naturally occurring sympathetic neurotransmitters are cate- cholamines known as norepinephrine, epinephrine, and dopamine. All three substances act within the ... Diatchenko and colleagues [10] also demonstrated that COMT inhibition in rats results in a dramatic increase in sensitivity to pain. Low COMT activity may increase pain sens...

Ngày tải lên: 09/08/2014, 10:21

... complementarity-determin- ing region (CDR3)- typing of T cells infiltrating the joints has been used, aiming to identify clones that are specifically enriched in the inflamed synovia. Some CDR3- ... S S E P S R F in nine out of 10 sequences starting with CASSE of 138 bases in length, and in only in one out of 21 sequences starting with CASSE of 141 bases and 144 bas...

Ngày tải lên: 09/08/2014, 13:22

... levels of proinflammatory cytokines and symptoms of RA, such as morning stiffness [11,12]. Several of these cytokines are highly elevated in patients with active RA in the early hours of the day, ... drugs at least in rheumatoid arthritis (RA) [1,6]. In addition, mild exercise and training and a decrease in the proinflammatory load – as obtained also by the use of an...

Ngày tải lên: 09/08/2014, 13:22