Báo cáo y học: " Lipocalin 2 is protective against E coli pneumonia" docx

... observed in the infected wild-type mouse compared to the uninfected wild-type mouse. As expected, no expression of lipocalin 2 was observed in the knock-out mice, regardless of whether they were ... 11:96 http://respiratory-research.com/content/11/1/96 Page 4 of 8 wild-type mice (Fig. 1I). To examine the effect of lipocalin 2 in the defence against pulmonary bacterial infections, we...

Ngày tải lên: 12/08/2014, 11:22

... interests. Received: 20 Nove mber 20 09 Revised: 2 February 20 10 Accepted: 18 May 20 10 Published: 18 May 20 10 References 1. Aird WC: The role of the endothelium in severe sepsis and multiple organ dysfunction ... Table 2 a nd Figure 1b), but the difference in VEGF between severe sepsis and sepsis without organ failure was not significant. Ang -2 and disease severity Ang -2 corre...

Ngày tải lên: 13/08/2014, 20:22

... increased CIDE-A expression precedes elevated blood glucose during the onset of obesity-induced type 2 diabetes.) Discussion While liver steatosis and its associated diseases represent an ever increasing ... the level of CIDE-A gene expression for the individual tissue as determined by DNA microarray analysis (ND: not determined). 0.87 6.77 2. 78 9. 92 24. 52 ND ND ND Liver Liver Heart...

Ngày tải lên: 13/08/2014, 13:20

... the primer C9LM*, respectively. Fragments generated are finally analysed by agarose gel (2% Metaphore + 2% agarose) electrophoresis (B). Lane 1, M olecular mass marker (pBR 322 digested by Hae ... of the sample analysed. Experimental strategy designed to analyse the new a s1 -Cas variant at the nucleotide level To determine the coding sequence of a gene, there are at least two possible strate...

Ngày tải lên: 22/02/2014, 04:20

... isomerase; CS, citrate synthase; G3PDH, glyceraldehydes-3-phosphate dehydrogenase. (Received 26 August 20 02, revised 7 October 20 02, accepted 15 October 20 02) Eur. J. Biochem. 26 9, 5931–5938 (20 02) ... Nine rats were fed a commercial rat chow replete with add dietary requirement and were given free access to water and food for 7 days before water-restriction. They were then divide...

Ngày tải lên: 08/03/2014, 09:20

... role, yet caspase -2 deficient mice have an extremely subtle phenotype, arguing against a non- redundant role in programmed cell death [6,7]. Caspase -2 has recently received considerable attention, ... was detected, in addition to the fully processed large subunit (Fig. 2B). Like the wild-type enzyme, the cleavage site mutant pro-caspase -2 D152A was processed efficiently between the larg...

Ngày tải lên: 23/03/2014, 13:20

... October 20 01, revised 30 January 20 02, accepted 14 March 20 02) Eur. J. Biochem. 26 9, 22 32 22 37 (20 02) Ó FEBS 20 02 doi:10.1046/j.14 32- 1033 .20 02. 028 81.x factors for hepatic gene expression [16]. The ... peptide of 21 residues. The peptide was reduced, alkylated, then re-analyzed by MALDI-TOF MS and Edman degradation. The eight blanks were determined to be cysteine residu...

Ngày tải lên: 24/03/2014, 03:21

... shown by this protein. Firstly, because this residue is required for the specific ribonuclease activity of the protein against ribo- somes. and secondly, because this residue is essential for the binding ... profiles were obtained by measuring the temperature dependence of the ellipticity at 22 0 nm in the range of 25 –85 8C; the temperature was continuously changed at a rate of 0.5 8C...

Ngày tải lên: 31/03/2014, 23:20

... stionnaire that measures affec- tive temperaments on five scales, the depressive, cyclothymic, irritable, anxious and hyperthymic tem- peraments [14 ,21 ,22 ]. All subjects were genotyped for 5-HTTLPR by ... psychometric scale to predict presence of the s allele by selecting the items which dif ferentiated between t he different genotype groups using analysis of variance (ANOVA) and performin...

Ngày tải lên: 08/08/2014, 23:21

... RA is associated with a reduced life expectancy, primarily because of excessive deaths from CV disease [21 -25 ]. RA is a heterogeneous dis- ease, and the disease phenotype itself is predictive ... hypercho- lesterolemia, hypertension under treatment, smoking history (yes or no), and type I or type II diabetes. We have selected variables in our analysis where the data sets were largely...

Ngày tải lên: 09/08/2014, 06:23