Báo cáo y học: "Inhibition of IFN-γ-dependent antiviral airway epithelial defense by cigarette smoke" pptx
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... Laemmli [32]. Assay of cell-free HA synthesis Cell-free HA synthesis was performed by a modification of the method reported by Nakamura et al. [18]. Analysis of the transfer of UDP-[U- 14 C] GlcUA ... treatment may cause a decrease in hyaluronan synthase activity by altering the lipid environment of membranes, especially the distribution of different cardiolipin species, surro...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot
... in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties. ... R.T. (1994) Glycosylphosphatidylinositols synthesized by asexual erythrocytic stages of the malarial parasite, Plasmodium falciparum. Candidates for plasmodial glycosylphosphatidyl...
Ngày tải lên: 31/03/2014, 23:20
Tài liệu Báo cáo khoa học: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles pptx
... School of Pharmacy, University of Bradford, UK 2 School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, UK Methionine synthase (MetS) (5-methyltetrahydrofolate- homocysteine ... cytosolic enzyme, methionine synthase (EC.2.1.1.13), catalyzes the remethylation of homocysteine to methionine using 5-methyltetrahydrofolate as the methyl donor. The products of t...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... the primary hereditary cardiomyopathy of the Syrian hamster. I. Regulation of prodynorphin gene expression by nuclear protein kinase C. J. Biol. Chem. 272, 6685–6692. 22. Ishizuka, S., Yano, T., ... cell proliferation of human mammary myoepithelial-like cells by hepatocyte growth factor/scatter factor depends on heparan sulfate proteoglycans and sustained phosphorylation of Ó FEBS...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by the substitution, as is often the case in ribozyme inhibition by tetracyclines [33,39,43]. In ... of chlorine for hydrogen at position 7 (Fig. 1C). Inhibition by Cl-tetracycline w as found to be sixfold more t han by tetracycline (Fig. 2). The extent of splicin...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... inhibition of platelet aggregation [6,7] and inhibition of inflammatory cytokine production in macrophages [8]. Curcumin has also been shown to affect the activity of a number of key enzymes such as cyclooxygenase ... fluorescence intensity represents quenching of the fluorescent dye by Co 2þ ions. Upon addition of curcumin, the rate of quenching is substantially increased and de...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition ppt
... & Kerenyi, T.D. (1971) Leucylglycinamide released from oxytocin by human uterine enzyme. Science 173, 827–829. 35. Shinoda, M., Miyazaki, A. & Toide, K. (1999) Effect of a novel prolyl endopeptidase ... Auerswald, E.A. (1995) Temporary inhibition of papain by hairpin loop mutants of chicken cystatin. Distorted binding of the loops results in cleavage of the Gly(9)-Ala10...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt
... permeability studies The effect of 2-APB on membrane permeability was monitored by assessing the quenching of calcein dye trapped in egg phosphatidylcholine liposomes by Co 2+ , as described by Longland ... the surface of the Ca 2+ -ATPase (Site B). As can be seen in Fig. 9, the loss of the hydroxyl group from the Tyr837Phe mutant enzyme resulted in a reduction of inhibition...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis" potx
... kDa glycoprotein that is synthesized in liver. The inhibitory activity of antithrombin on thrombin is signifi- cantly enhanced by heparin, a type of glycosaminoglycan (GAG) [8]. The GAG family comprises ... 4 Effects of various metal ions on ability of hyaluronic acid (HA) to inhibit the activity of antithrombin (AT)Effects of various metal ions on ability of hyaluronic acid (...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice" docx
... of synthetic peptides was not significantly affected by the inhibitors used (Figure 5c,d). Anti- gen presentation by DCs was also inhibited by cytochalasin D, amiloride or DMA, but not by monodansylcadaverine ... higher efficiency compared with macrophages and there was no dif- ference between the glycosylated and non-glycosylated epitope presentation. Mean fluorescence intensity an...
Ngày tải lên: 09/08/2014, 08:22