Báo cáo y học: "Cytosolic phospholipase A2α mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice" potx
Báo cáo y học: "Cytosolic phospholipase A2α mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice" potx
... provided the original work is properly cited.
Research
Cytosolic phospholipase A2α mediates
Pseudomonas aeruginosa
LPS-induced airway
constriction of CFTR -/- mice
Yong-Zheng Wu
1,2
, Mohammad Abolhassani
3
, ... the
induction of airway constriction in CFTR -/- mice. Our
studies suggest that cPLA2α, which catalyzes the key step
of AA release, plays a role...
Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf
... Biochemistry and Microbiology, University of Leeds, UK
Cytosolic phospholipase A
2
-a (cPLA
2
-a) is an 85 kDa
protein that specifically cleaves the sn-2 fatty acyl of
phospholipid to liberate free fatty ... potent vasodilator and inhibitor of platelet activation,
through the action of cyclooxygenase (COX) enzymes. Here we study the
relocation of cPLA
2
-a in human EA.hy.926 endoth...
Báo cáo y học: "HLA-C locus alleles may modulate the clinical expression of psoriatic arthritis" potx
... population of 177 random donors
from our general population. DNA was isolated from lym-
phocytes by standard procedures. HLA-C alleles were specif-
ically amplified with a combination of the sense ... for 50 seconds (50 cycles), with a
initial denaturation step of 98°C for 1 minute and a final exten-
sion step of 70°C for 5 minutes. The specificity of the PCR-
SSOP (polymerase chain...
Báo cáo y học: " Estrogen aggravates inflammation in Pseudomonas aeruginosa pneumonia in cystic fibrosis mice" potx
... thereby adequately hydrate the airway
surface liquid. A widely held hypothesis to explain the
predisposition of CF airways to chronic infection is that
reduced volume of isotonic periciliary airway ... Chronic infection of CF airway by
P. aeruginosa is associated with the formation of bio-
films [31]. Since neutrophils enhance the formation of
P. aeruginosa biofilms [32],...
Báo cáo y học: " Global gene expression patterns in the post-pneumonectomy lung of adult mice" ppt
... day, 3 days and 7 days) post-pneumonectomy
spanning the period during which the bulk (>80%) of
lung regeneration occurs, as measured by changes in vital
capacity [12]. Following analysis of ... genes were
differentially expressed between PNY and SHAM at 6
hour, 1 day, 3 day and 7 day post-pneumonectomy
respectively (complete data not shown), with an S-score
of ≥ 3 or ≤ -3 (equivalent...
Báo cáo y học: " Maximal respiratory static pressures in patients with different stages of COPD severity" potx
... maxi-
mal inspiratory pressure) is the most widely used and is a
simple way to gauge respiratory muscle strength and to
quantify its severity [1-3].
When we analyze maximal respiratory pressure, we
should ... study
did not find any correlation with weight and age, proba-
bly because our patients had reached approximately 60
years of age with the same normal body weight.
For these reasons ou...
Báo cáo y học: " A self-rating scale for patient-perceived side effects of inhaled corticosteroids" potx
... unpleasant feeling in your throat Oropharyngeal Itching – 2 items:
• a dry throat • an itchy feeling on the roof of your mouth
• an itchy feeling in the back of your throat
Oropharynx Problems – 9 ... item:
• any form of dental decline (tooth decay, tooth staining etc.)
Skin, Hair and Nails – 7 items:
• dry skin Eye Dryness – 1 item:
• dry skin on the face • dry eyes
• bruising easily
•...
Báo cáo y học: "Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial" docx
... work is properly cited.
Pseudomonas aeruginosa virulence<p>Sequencing of a highly virulent strain of <it> ;Pseudomonas aeruginosa </it>and comparison to a previously sequenced, ... detailed description of the contents of
the table and serves as a legend for the first worksheet.
Additional data file 1Summary of supplementary methodsSummary of supplementary m...
Báo cáo y học: " Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro" ppsx
...
cluster of group IVA phospholipase A
2
(Lys488/Lys541/Lys543/Lys544)
is involved in translocation of the enzyme to phagosomes in human
macrophages. J Lipid Res 2009, 51(2):388-99.
31. Meliton AY, ... design of the study, and
to the manuscript writing. NMM and AYM performed the data analysis. AYM
and LNM performed the assays for gIVaPLA
2
enzyme activity, PMN migration, F-
actin p...
báo cáo hóa học: " Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis" potx
... are likely to be interactions of the PLA2
enzymes with elements of antigen-specific immunity. Fur-
thermore, sPLA2s influence levels of proinflammatory
cytokines in a variety of cell types (either ... contribution of the innate immune system to
multiple sclerosis (MS), including the activity of acute inflammatory mediators. The purpose of this
study was to test the involvement...
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