Báo cáo y học: " Effects of Liver × receptor agonist treatment on signal transduction pathways in acute lung inflammation" potx

... the role of the LXR receptor in the pathophysiology of acute inflammation. Our results imply that LXR agonists may be useful in the therapy of inflammation. Abbreviations (L×R): Liver × receptor; ... as: Crisafulli et al.: Effects of Liver × receptor agonist treatment on signal transduction pathways in acute lung inflammation. Respiratory Res...

Ngày tải lên: 12/08/2014, 11:20

... assessed by tonometry, and do not affect systemic hemodynamics in most patients with ARDS. This is consistent with the findings of two other studies on the effects of PEEP on splanchnic perfusion in ... changes in cardiac index or in CO 2 gap were found at any of the study periods (Table 2). Oxygenation index, mean arte- rial pressure, pulmonary mean arterial pressure, pu...

Ngày tải lên: 12/08/2014, 20:20

... concentrations of pro-inflammatory cytokines. Glucocorticoid treatment of cartilage can effectively abolish matrix degradation induced by the combination of pro-inflammatory cyto- kines and injury. We ... 5 of 15 Conclusions Acute knee injury initiates cascades of catabolic events in joint tissues, including mechanical disruption of carti- lage matrix and increasing synovial...

Ngày tải lên: 12/08/2014, 18:20

... IPC, ischemic preconditioning + 30 min of ischemia. IPO, 30 min ischemia + ischemic postconditioning. IPC+IPO, ischemic preconditioning + 30 min of ischemia + ischemic postconditioning. Knudsen et ... ischemic postconditioning. World J Gastroenterol 2004, 10:1934-1938. 16. Wu BQ, Chu WW, Zhang LY, Wang P, Ma QY, Wang DH: Protection of preconditioning, postconditioning and combined thera...

Ngày tải lên: 13/08/2014, 13:20

... The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 1961, 93:440-447. 27. Beutler E, Duron O, Kelly BM: Improved ... irradiation dose rate was 0.61 Gy/min. Animals (whole body) were exposed to 2 Gy per week at a total dose of 8 Gy, one day after TAA adminis- tration. Induction of liver fibrosis Li...

Ngày tải lên: 13/08/2014, 15:21

... cognitive effects of benzodiazepines after subchronic treatments [1]. Interestingly, subchronic treatment of ethyl loflaze- pate did not prolong the latency in spite of its long elimination rate. Finally, ... memory in the neuropsychological tests. Secondly, subchronic treatment with drugs produced prolongation in P300 latency only in th e Fz regions. Weak prolongation in...

Ngày tải lên: 09/08/2014, 01:21

... fol- lowing reasons: 1) Direct delivery of therapeutic agents in the site of infection is advantageous pharmacokinetically. Only limited amounts of systemically administered IgGs (intravenously, or intramuscularly) ... administration of P. aerugi- nosa (5 × 10 7 CFU) for an interval (4 h) consistently leads to modest quantities of lung injury. Using independent measurement...

Ngày tải lên: 11/08/2014, 10:23

... lipo- dystrophy result in a good outcome [45], as well as having beneficial effects on the immune system such as inducing thymocyte differentiation, improving function of lym- phocytes, increasing ... at inducing virus-specific CD4 + and CD8 + T-cell responses, in chronic HIV-1 infection [1]. Here we assessed the effects of rhGH therapy on the immune sys- tem of chronically...

Ngày tải lên: 11/08/2014, 10:23

... motoneurone excitability or to presynaptic inhibition, probably resulting from thin afferent fiber (group III-IV) signaling which may have been sensitized by the production of pro-inflammatory ... made in an attempt to reproduce habitual race conditions since the main aim of this study was to investigate if ingestion of an association of CHOs, BCAAs and caffeine was useful in...

Ngày tải lên: 11/08/2014, 23:21

... corresponding signaling pathways, we fur- ther elucidated the involvement of different signaling pathways in regulating expression of adhesion molecules and chemokines of FLS. These inhibition experiments demonstrated ... molecules and chemokines indicates the dis- tinct signaling pathways in inflammatory responses. Such induction of chemokines by IL-27 in RA-FLS was not co...

Ngày tải lên: 12/08/2014, 14:22