Báo cáo khoa học: "Herpes simplex virus infection in pregnancy and in neonate: status of art of epidemiology, diagnosis, therapy and preventio" potx

... viral transmission [51]. Intrauterine HSV infection is a rare disorder and accounts for 5% of HSV infections in neonates. The highest risk of intrauterine infection has been observed in pregnants (about ... lethal in 6% of cases leaving 69% of permanent late sequelae. The disseminated infection takes a lethal course in 31% and has late sequelae in 17% of cases [3...

Ngày tải lên: 12/08/2014, 04:21

... distribution in the cytoplasm at 6 h postinfection (Fig. 4A), and increased both in the perinuclear region and in the peripheral region at 9 h postinfection (Fig. 4B). The pattern of the intracellular ... role in the intracellular transport and/ or release of virions after for- mation of infectious virions. We thus investigated single- step growth kinetics of extracellula...

Ngày tải lên: 12/08/2014, 04:20

... transported. Pulmonary inflammation, of whatever cause, increases the PLI up to four times normal values in the most severe forms of lung injury, including ARDS. In less severe injury, such as impending ARDS and interstitial ... viral shedding and spread, which could inform the decision regarding whether to institute antiviral therapy and help in determining the pathogenicit...

Ngày tải lên: 12/08/2014, 20:20

... experiments and participated in drafting the manuscript, VNC participated in the construc- tion and characterization of the viruses, AB was involved in the design and conduction of in vivo studies, ... monolay- ers of Vero (a) and 4T1 (b) cells were infected at an MOI of 2 with each virus, incubated at 37°C and the numbers of infec- tious virions were determined...

Ngày tải lên: 20/06/2014, 01:20

... multiplicity (moi) of infection of 1 and 5, and the infections pro- ceeded at 37°C in RPMI 1640 medium with 10% fetal calf serum (FCS). Cells and culture media were collected at early and late time point of infection ... (F) and the deletion viruses in U937 cells. Conclusion In the present study, we show that the HSV-1 infection increased the mRNA expression of T...

Ngày tải lên: 20/06/2014, 01:20

... ligases: an amino-terminal C2 domain; four protein-protein interacting WW domains, which most commonly recognize PY motifs of binding pro- teins; and a carboxyl terminal catalytic HECT domain (Fig. ... pathway and partially via the ubiquitin-protea- some pathway in the course of HSV-2 infection. UL56 interacted with Itch and induced the degradation of Itch independent of any...

Ngày tải lên: 12/08/2014, 04:20

... samples and par- ticipated in the screening of samples for HCV. G.O.A: Col- lected samples and participated in the screening of samples for HCV. A.A.C: Participated in the design and coordination of ... with HCV infection develop diabetes because the pathogenic mechanisms leading to DM in patients with HCV infection are still not well understood. Both insulin resistanc...

Ngày tải lên: 12/08/2014, 04:21

... validate our findings and to analyse in more detail the clinical and the epidemiological features of this infection and to evaluate the cost-effectiveness of antenatal HEV screening in Ghana. Consent Fully ... importance and pathogenesis of HEV infection among pregnant women engaged in different occupations. The policy of not screening for HEV antibodies in preg- n...

Ngày tải lên: 12/08/2014, 04:22

... samples and par- ticipated in the screening of samples for HCV. G.O.A: Col- lected samples and participated in the screening of samples for HCV. A.A.C: Participated in the design and coordination of ... rate of HCV replication. Plasma levels of pro inflammatory cytokines like tumor necrosis factor- alpha are increased in acute alcoholic hep- atitis and such cytokines...

Ngày tải lên: 12/08/2014, 04:22

... claudin-1 in not a determinant of specie host range of the virus. Down reg- ulation of claudin-1 via siRNA resulted in a decrease in infection levels of HCVpp and HCVcc [111]. The n-terminal 1/3 of ... transmembrane proteins and regulate post-ligand binding events, including integrin- mediated adhesion strengthening. The c-terminus of CD81, CD151, and other tetraspa...

Ngày tải lên: 12/08/2014, 04:21