Báo cáo khoa học: " The inhibition of assembly of HIV-1 virus-like particles by 3-O-(3'''''''',3''''''''-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain" pdf

... which suggests that PhyH-DI has the capacity to increase the catalytic efficiency of PhyH-DII. Further- more, the catalytic efficiency of PhyH was much greater than that of PhyH-DI and PhyH-DII combined ... was basically stable at 35 °C, and retained 60% of the initial activity at 45 °C for 90 min when assayed at 35 °C (Fig. 3A, B). The presence of Ca 2+ increas...

Ngày tải lên: 14/02/2014, 15:20

... significant role in the protection of A n B n GAPDH isoforms against oxidative stress. Discussion The aims of the present study were to establish whe- ther chloroplastic GAPDH isoforms undergo gluta- thionylation ... thioredoxin-independent isoform of chloroplastic glyceraldehyde-3-phosphate dehydrogenase is selectively regulated by glutathionylation Mirko Zaf...

Ngày tải lên: 19/02/2014, 05:20

... the Sm complex. Mol. Cell 7, 319–329. Ó FEBS 2004 The role of the C-terminal domain on Hfq (Eur. J. Biochem. 271) 1265 The C-terminal domain of Escherichia coli Hfq increases the stability of ... On the basis of these results, we propose that the C-terminal domain could protect the interface between the subunits and stabilize the hexameric...

Ngày tải lên: 19/02/2014, 12:20

... features of the processing system and thus provide an empirical validation of the approach. Most interestingly, the sensitivity of human processing to the degree of regularity and frequency of ... resolution of these issues. In this paper, we present a descriptive analysis of the grapheme-phoneme mapping system of the French orthography, and we further exp...

Ngày tải lên: 20/02/2014, 19:20

... Biochem. 270) 3905 The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774 Re-evaluation of the spectroscopic data ... core description and the spectroscopic and redox properties of each identified heme from the NrfHA complex. Conclusions D. desu...

Ngày tải lên: 21/02/2014, 00:20

... of data on problem solving and talk about problem solving, 2) development of a process model of these behaviors, and 3) use of coding techniques to extract traces of "critical phenomena" ... model of the role of point of view in problem solving. SUMMARY We have reported here a three pronged approach to the study of problem solving action and repor...

Ngày tải lên: 21/02/2014, 20:20

... both distantly related to domain V of the DNA polymerase III s subunit Ke˛stutis Timinskas and C ˇ eslovas Venclovas Institute of Biotechnology, Vilnius University, Lithuania Keywords clamp loader; ... revealed that the N-terminal region of the bacterial replicative polymer- ase PolC includes two structural domains: PolC- NI and PolC- NII. Both do...

Ngày tải lên: 05/03/2014, 23:20

... type S. cerevisiae Drosophila Human Catalytic subunit Pph3p Ppp4c ⁄ Pp4 ⁄ cmm Ppp4c ⁄ PP4 ⁄ PPX Core regulatory subunit of Pph3 ⁄ Ppp4c YBL 046 w ⁄ Psy4p R2 R2 Regulatory subunit of Pph3 ⁄ Ppp4c Psy2p ... examine the properties of the putative S. cerevisiae R2 orthologue, YBL 046 w, and show that deletion of YBL 046 w, similarly to deletion of PPH3, con...

Ngày tải lên: 07/03/2014, 12:20

... that of the WT protein. Only these vari- ants of GM2AP were examined in all further studies. To assess the potential of the variant GM2AP forms for the stimulation of HexA catalysed hydrolysis of GM2, ... to map the protein region on GM2AP responsible for binding to the enzyme and to further elucidate the activator’s mode of action at the lipid–water interface...

Ngày tải lên: 07/03/2014, 12:20

... averages of three measurements. Ó FEBS 2004 Two FMN groups in NAD + -reducing [NiFe]-hydrogenase (Eur. J. Biochem. 271) 805 Selective release and function of one of the two FMN groups in the cytoplasmic ... demonstrate that the release or re-binding of flavin at the FMN- a binding site occurs only in reduced enzyme and that FMN...

Ngày tải lên: 07/03/2014, 15:20

... regions of the L protein. D. Yu et al. Bio-nanocapsules for protein delivery FEBS Journal 272 (2005) 36513660 ê 2005 FEBS 3653 The specific delivery of proteins to human liver cells by engineered bio-nanocapsules Dongwei ... (Fig. 5B). Human hepatocyte specific delivery of EGFP by infection The preS1 peptide displayed on the surface of L parti- c...

Ngày tải lên: 23/03/2014, 15:20

... FTI-induced p27Kip1 increase and G1 arrest (Eur. J. Biochem. 270) 2765 The inhibition of Ras farnesylation leads to an increase in p27 Kip1 and G1 cell cycle arrest Hadas Reuveni*, Shoshana Klein ... process. HR12 induces arrest of Rat1 /ras cells at the G1 phase of the cell cycle We next examined the effect of HR12 on the distri...

Ngày tải lên: 31/03/2014, 01:20

... Laboratory for Computer and Communications Research, Simon Fraser University, Burnaby, B.C., Canada. March 1985. 199 The detection and representation of ambiguities of intension and description ... that since the filler of the role Queen of England is not likely to change within the time of the conversation and the speaker, the hearer, and Nadia are all awa...

Ngày tải lên: 31/03/2014, 17:20

... Open Access The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP9 0A and HSP90B1 Saad Z Usmani 1* , Robert D Bona 2 , Gabriela Chiosis 3 , Zihai ... cytosolic HSP90 (HSP90AA1), the ER paralogue gp96 (HSP90B1) and the mitochondrial member TRAP1 (HSP90L). We evaluated the in vitro anti-tumor activity an...

Ngày tải lên: 10/08/2014, 22:21

... (Fig. 6Bii, and Fig. 6C). These results suggested that the antagonistic activity of Vif against the DSB inhibition of Gag assembly, absent from VifS116V and VifC133S mutants, was associated with the ZBD ... effect of packaging-defective mutant Vif subC on the DSB inhibition of HIV-1 VLP assemblyFigure 5 Counteracting effect of packaging-defective mutant Vif...

Ngày tải lên: 12/08/2014, 04:21