Báo cáo y học: "Detection of novel insect flavivirus sequences integrated in Aedes albopictus (Diptera: Culicidae) in Northern Italy" potx

... transmitted by Aedes albopictus (Diptera: Culicidae) in the Autono- mous Province of Trento. Principal Investigator: David Roiz. This study was also supported in part by the Spanish Ministry of Science ... will help to clarify the nature, origin and evolution of the flavivirus genus. It is important to analyze more thoroughly whether the pres- ence of insect flaviv...

Ngày tải lên: 12/08/2014, 04:21

... transmitted by Aedes albopictus (Diptera: Culicidae) in the Autono- mous Province of Trento. Principal Investigator: David Roiz. This study was also supported in part by the Spanish Ministry of Science ... will help to clarify the nature, origin and evolution of the flavivirus genus. It is important to analyze more thoroughly whether the pres- ence of insect flaviv...

Ngày tải lên: 12/08/2014, 04:22

... PrP c . This interaction via binding to the hydrophobic domain of PrP c then inhibits the toxicity of the C-terminus. The normal N-terminal domain of the C-terminal cleavage product of PrP c is ... other’s toxicity in the intact protein. Point mutations in the inherited forms of disease might have their effects by diminishing this inhibition. Keywords: prion; neurotoxicity; circ...

Ngày tải lên: 31/03/2014, 23:20

... [14]. Furthermore, peptidylarginine deiminase (PAD) generates citrulline residues by deimination of arginine residues of proteins. Isoforms 2 and 4 of PAD were expressed in mononuclear cells isolated ... organization of the actin cytoskeleton in vivo [47-50]. Therefore, citrullination of CapZα-1 may inhibit the activity of capping protein and can lead to degeneration of vari...

Ngày tải lên: 09/08/2014, 08:23

... 5 of 8 (page number not for citation purposes) The even higher agreement (87% vs 77%) between CT and MRI in a study of nine RA wrist joints by Perry and colleagues [12] may partly be explained ... comparison of CT and MRI volumes. *P < 0.01. a Intramodality agreement, reading A minus reading B; intermodality agreement, CT erosion volume minus MRI erosion volume. b Intramodality a...

Ngày tải lên: 09/08/2014, 10:23

... protein, synthesized by cells lining synovial joints. J Orthop Res 1999, 17:110-120. 40. Schmidt TA, Schumacher BL, Klein TJ, Voegtline MS, Sah RL: Synthesis of proteoglycan 4 by chondrocyte subpopulations ... pattern of HSPGs has recently been shown to be critical for determining the specifi- city and affinity of binding to growth factors and morphogens [36]. The sulfation patterns of...

Ngày tải lên: 09/08/2014, 10:23

... the symptoms of MSU crystal inflammation by enhancing both inflammation and pain in affected joints. The enzyme Hdc converts histidine to histamine. Histamine is elevated in the joint fluid of ... point as the peak of a rapid, early surge in proinflam- matory cytokine and immediate early gene transcription. In agreement with the induction of IL-6 mRNA in the mem- brane, anal...

Ngày tải lên: 09/08/2014, 10:23

... [12]. Ubiquitination reactions are involved in diverse biological functions, including regulating receptor tyro- sine kinase signaling by modulating endocytosis and degrada- tion of activated ... deviation; SNP: single-nucleotide polymorphism; UBA: ubiquitin-associated domain; UBAC2: ubiquitin-associated domain containing 2; UBASH3A: ubiquitin asso- ciated and SH3 domain containing, A; U...

Ngày tải lên: 09/08/2014, 14:20

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Ngày tải lên: 09/08/2014, 20:22

... evaluation of DNA demethylation and cytotoxicity in living cells, thus providing an expedient screening platform for identifying demethylating agents. As the exact mode of action of procainamide in decreas- ing ... effect by inhibiting DNA methyltrans- ferases (DNMTs), the key enzymes responsible for initiat- ing or maintaining the DNA methylation status, thereby facilitating the re...

Ngày tải lên: 10/08/2014, 05:21