Báo cáo khoa học:" The directionality of the nuclear transport of the influenza A genome is driven by selective exposure of nuclear localization sequences on nucleoprotein" pptx

... mechanism that regulates the directionality of the nuclear trafficking of influenza vRNPs. We conclude that selective exposure and masking of the NLS1 on the vRNP constitutes a critical mechanism ... Central Page 1 of 12 (page number not for citation purposes) Virology Journal Open Access Research The directionality of the nuclear transport of the...

Ngày tải lên: 12/08/2014, 04:21

... purpose, forward primers 5¢-CGACTCGA GAAAAGAGCGCAAGAGCCAGTCAA-3¢ and 5¢-CGAC TCGAGAAAAGAGCTGTCACGGGAGTTCCT-3¢ were used for amplification of the elafin and the trappin cDNA 5¢ end, respectively, and reverse ... enzymes, the reaction being described by an association and a dissociation rate constant and E þ I Ð k ass k diss EI an equilibrium dissociation constant K i ¼ k diss ⁄ k ass...

Ngày tải lên: 19/02/2014, 07:20

... 6B) and absence (data not shown) of conca- navalin A. Discussion Eugenin is the only peptide detected in aqueous extracts of pouch swabs of the Tammar wallaby. Euge- nin has a sequence related ... Two of these (a and b cleavages) are fragmentations of amide moieties, and give infor- mation analogous to that provided by B and Y+2 cleavages in the corresponding positive...

Ngày tải lên: 19/02/2014, 16:20

... Model of the regulation of the Abd-B gene in abdominal segments A6 and A7 . Although the iab-5 cis-regulatory region is also in an active conformation in A6 , only iab-6 is presumed to contact the Abd-B promoter ... between iab-7 and iab-8. This assumption is compatible with the location of the PTS. The discovery and characterization of the PTS in a transgen...

Ngày tải lên: 20/02/2014, 01:20

... returning it plus an additional ball of the same color to the urn. In an adaptor grammar there is one DP for each adapted nonterminal A ∈ M, whose base distribu- tion H A is the distribution over trees ... segmentation accuracy. Modeling syllable structure is a natural application of adaptor grammars, since the grammar can learn the possible onset and coda clusters,...

Ngày tải lên: 20/02/2014, 09:20

... because, such a distinction is prevalent in many other sounds, some of which are (a) nasals in Tamil (Shanmugam, 1972) and Malayalam (Shanmugam, 1972; Ladefoged and Maddieson, 1996), (b) laterals ... indicates that the speakers of l are unable to make a distinc- tion as to whether c is articulated with the tongue against the upper teeth or the alveolar ridge. In contrast,...

Ngày tải lên: 22/02/2014, 02:20

... muscles caused increased formation of ATP, we examined the effect of carbachol, a stable analog of acetylcholine, on the spontaneous overflow of ATP. Carbachol (1 lm) caused no additional formation of ... Ca 2+ concentra- tion [37,47]. Modulation of spontaneous discharge at the level of the release machinery is not always accompanied by corresponding modulation o...

Ngày tải lên: 05/03/2014, 23:20

... [ibuprofen], respectively, and k þ off is the k off value obtained in the absence of ibuprofen. Data analysis Kinetic and thermodynamic data were analyzed with the matlab program (The Math Works, Natick, MA, USA). The ... cleft FA1 and the ligand-binding pockets FA2 and FA6, all located in domains I and II of (t)HSA. Abbreviations FA, fatty acid; HSA, human serum albumin; HSA...

Ngày tải lên: 06/03/2014, 01:20

... possi- ble functional implications of the behavior of this loop. The first is the facilitation of the conformational rearrangements and the maintenance of the conforma- tional plasticity for effective ... there is no substantial change in the conformation of the protein or in the distribution of the conformational ensemble of the GGQ loop. In contrast to...

Ngày tải lên: 07/03/2014, 05:20

... (ATA) to Lys (AAA), Leu645 (CTA) to Arg (CGA), Ser649 (TCG) to Lys (CGC), Asn651 (AAC) to Lys (AAA), Gln653 (CAA) to Lys (AAA), and Asn656 (AAT) to Lys (AAA). Each mutation was created from the ... x is the proportion of the ith amino acid of the 20 standard amino acids at that location [20]. The value is similar to that obtained for gene diversity in population genetics [21...

Ngày tải lên: 07/03/2014, 05:20