Báo cáo khoa học:" Properties of virion transactivator proteins encoded by primate cytomegaloviruses" doc

... surprising dissimilarities in the properties of primate cytomegalovirus UL82 homologs, despite the fact that each of the proteins is a potent transactivator of IE gene expression. The close rel- atives, ... that the YFP moiety does not affect the functional properties of the proteins [21,24,33]. The functional activities of the proteins were determined by infecting U...

Ngày tải lên: 12/08/2014, 04:21

... M UL82 Actin BioMed Central Page 1 of 12 (page number not for citation purposes) Virology Journal Open Access Research Properties of virion transactivator proteins encoded by primate cytomegaloviruses Iain ... important for the role of pp71 in activation of gene expression. The intranu- clear localization of the UL82 homologs was investigated by immunofluorescence a...

Ngày tải lên: 12/08/2014, 04:21

... to identify the modification induced by H 2 O 2 , but the similarity of the behavior of several amine oxidases suggested that it consists of the oxidation of a conserved residue at the active ... consumed by an excess of amine in a closed cuvette, or the amine was consumed by oxygen in a solution stirred in air, with the rapid turnover of a thousand-fold amine excess. Further...

Ngày tải lên: 19/02/2014, 12:20

... adverse outcomes. P16 p16 belongs to the CDKN2A family of proteins, another family of CDK inhibitors [18,52]. This family of proteins particularly inhibits the activity of active CDK4 and CDK6 [52]; thus, their ... cancer. p21, p27, p57, p16 These proteins are part of the CDKN1A family; a family of proteins which broadly inhibits the activity of CDKs. As illustrated in fi...

Ngày tải lên: 09/08/2014, 03:21

... alignment of N-terminal (A ⁄ B) domains of LdEcR and DmEcR. (A) Alignment of EcRA from the two species. (B) Alignment of DmEcRB1, DmEcRB2, and LdEcRB. (C) Alignment of most carboxy-terminal side of ... Graduate School of Agriculture, Kyoto University, Japan 4 Institute of General Zoology and Endocrinology, University of Ulm, Germany Insect development is largely driven by...

Ngày tải lên: 18/02/2014, 08:20

... database with a protein score of 540, peptide X corr values up to 5.7 and a sequence coverage by amino acids of 54.6%. Effect of temperature and pH on the stability of NADPH Because NADPH is not ... under the conditions present in the cyto- plasm of Picrophilus. The kinetics of NADPH degradation was followed by measuring the rate of decrease of its absorbance at 340 nm ove...

Ngày tải lên: 19/02/2014, 16:20

... not contain detectable amounts of this un usual stereoisomer of 18:2. In order to investigate if the synthesis of this E isomer of 18:2 in C. alpina seed was a product of t he C. alpina D12 acetylenase ... spots) were scraped off and methylated in situ with 0.1 M sodium methoxide . Fatty acid methyl esters of total lipids from chloroform extracts of yeast cells were prepared by...

Ngày tải lên: 16/03/2014, 18:20

... possibly be at the root of the ability of HzTrypsin-S to avoid inhibitor binding. Properties of the purified proteins as reported here are essential to our understanding of the way successful insects deal ... bands, and we did not observe any protein of a pI corresponding to SKTI (which is around 5 for different isoforms of SKTI). Identity assignment of trypsins by MS To li...

Ngày tải lên: 23/03/2014, 20:22

... unfold- ing of the a-helix from the body of the b-sheet (Fig. 2C). Possible role of domain-swapping in the ‘off-pathway folding’ (OFF) model The OFF model for amyloid formation was first described by Pallitto ... our understanding of the importance of different parts of the molecule and their flexibility in the process of amy- loid fibril formation often results more from a struc...

Ngày tải lên: 14/02/2014, 18:20

... deamination [30]. The lack of oxida- tion of 1 mm glutamate in the presence of 5 mm succinate can be demonstrated by a complete lack of effect of rotenone on recordings of membrane poten- tial from ... mediated by a relief of inhibition by cyclophilin D was evident in the form of slightly increased respiration rates during arsenolysis. However, the modulation of F 0 F...

Ngày tải lên: 14/02/2014, 19:20