Báo cáo khoa học: "Increased susceptibility of Huh7 cells to HCV replication does not require mutations in RIG-I" doc

... paren- tal Huh7 cells, suggesting that the HCV replicon replicates better in Huh7D cells relative to Huh7 cells. The increased susceptibility of Huh7D cells to HCV- replicons is independent of the ... are no amino-acid substitutions in the RIG-I coding region from Huh7D cells In order to determine if the increased susceptibility of Huh7D cells to HC...

Ngày tải lên: 12/08/2014, 04:21

... apomyoglobin [12], tropomyosin [13] or synthetic proteins [14]. Hydrostatic pressure is increasingly being used in the study of protein folding, misfolding, aggregation and transitions. In comparison ... result of unfolding, dissociation or aggregation of the intact enzyme [16]. In uence of temperature on enzyme inactivation by pressure treatment The in uence of temperature on...

Ngày tải lên: 07/03/2014, 03:20

... glucose- induced insulin secretion and insulin resistance in the liver and periphery. Hepatic insulin resistance is attrib- uted to a range of metabolic defects, which include impaired glucose tolerance ... synthesis, hepatocyte monolayers were incubated for 3 h in MEM con- taining [U- 14 C]glucose and 10 mm glucose unless otherwise indicated, without or with inhibitors as indicated....

Ngày tải lên: 30/03/2014, 11:20

... to imaginary spoon Touch ND side of table (approx. 7 inches from edge and 7 inches from midline) Event 2 Bring spoon to bowl to scoop pudding Pretend to scoop pudding from imaginary bowl Touch ... Imagined Object Absent Event 1 Reach to cup Reach to imaginary cup Touch center of table (approx. 10 inches from edge) Event 2 Bring cup to mouth (drink) Pretend to drink from...

Ngày tải lên: 11/08/2014, 14:20

... an inhibitor of c-Jun N-terminal kinase, showed no effect on the DNA binding of c-Fos and c-Jun induced by treatment with ATZ + mercaptosuccinic acid, indicat- ing that JNK is not involved in ... mutating the AP-1-binding site in the bim promoter region. Whereas the amounts of total and phosphory- lated c-Fos increased in the presence of ATZ + mer- captosuccinic acid, there wa...

Ngày tải lên: 06/03/2014, 00:21

... chain folds into two domains, with the small domain having a mixture of a-helices and b-sheets, and the large domain having an a ⁄ b-barrel structure (Fig. 8D). The binding of sub- strate brings ... denatured states of r-Pfen and Yen are shown in Fig. 7B,D. For both of these enzymes, disso- ciation of enolase into monomers led to a decrease in emission intensity. In the case...

Ngày tải lên: 23/03/2014, 09:20

Ngày tải lên: 07/08/2014, 15:20

... suppression of nitric oxide generation in an autocrine or a paracrine manner. OPN requires the presence of its receptor on the cell surface for internalization into brain cells. CD44 has been shown to ... receptor of OPN [2]. It was weakly expressed in the white matter of the normal spinal cord in our previous study [13] and in the present study. In rats having spinal cor...

Ngày tải lên: 07/08/2014, 18:20

Ngày tải lên: 07/08/2014, 18:21

... study, the involvement of caveolin-1 in an irradiation injured spinal cord was exam- ined by analyzing the phosphorylation of caveolin-1 in the spinal cord of rats after irradiation with a single ... 5 Department of Biochemistry, College of Medicine, and 6 Department of Nuclear and Energy Engineering, College of Engineering, Cheju National University, Jeju 690-756, Korea...

Ngày tải lên: 07/08/2014, 20:23