Báo cáo khoa học: " The role of mutations in core protein of hepatitis B virus in liver fibrosis" pdf

... [28]. To explain the < /b> effect of < /b> mutations < /b> of < /b> core < /b> protein < /b> in < /b> the < /b> biological process of < /b> the < /b> cell, we predicted the < /b> major func- tions of < /b> the < /b> core < /b> protein < /b> of < /b> hepatitis < /b> B virus. Protein < /b> pre- diction ... shown in < /b> Table 2. Association of < /b> Core < /b> Protein...

Ngày tải lên: 12/08/2014, 04:21

... positioning within subsite )1 [13]. Nevertheless, details about the < /b> role < /b> of < /b> different resi- dues of < /b> the < /b> aglycone-binding site in < /b> the < /b> stabilization of < /b> ES à and the < /b> interdependence between the < /b> binding ... of < /b> the < /b> glycone within the < /b> Sfbgly active site. This hypothesis was further investigated by deter- mi...

Ngày tải lên: 18/02/2014, 17:20

... is stabilized through the < /b> exchange between subunits of < /b> either their N-ter- minal, or their C-terminal ends [33–35]. We found that the < /b> behavior with the < /b> model membrane of < /b> the < /b> dimer in < /b> which the < /b> ... owing to the < /b> four carboxylates of < /b> residues Asp38 and Glu111. In < /b> RNase-AA-GG the < /b> ‘basic sur- face’ is more similar...

Ngày tải lên: 19/02/2014, 06:20

... defective in < /b> this disorder is also a NHEJ protein.< /b> The < /b> distinct clinical features of < /b> the < /b> patients will be discussed in < /b> the < /b> context of < /b> the < /b> protein < /b> function. 3.4 Diabetes, Obesity and Metabolic Syndrome S3.4-1 Integration ... leads to the < /b> generation of < /b> recombino- genic intermediates. DNA recombination enables th...

Ngày tải lên: 19/02/2014, 07:20

... the < /b> exception of < /b> the < /b> PSST subunit, found in < /b> the < /b> CCL16 -B2 mutant, but not in < /b> the < /b> o thers. Two i ntegral membrane proteins in < /b> the < /b> integral membrane-subcomplex b [2] could be monitored. The < /b> B1 7 protein < /b> was ... still be determined whether its absence in < /b> the < /b> V79-G18 mutant is the < /b> result of < /b...

Ngày tải lên: 19/02/2014, 16:20

... that N-glycans, in < /b> particular their terminal structures, are involved in < /b> regulating the < /b> GABA translocation of < /b> GAT1, but not in < /b> binding of < /b> GAT1 to GABA. Transport of < /b> GABA by GAT1 across the < /b> cell mem- brane ... GAT1 In < /b> order to gain further insight into the < /b> role < /b> of < /b> the < /b> terminal structures of < /b> the...

Ngày tải lên: 19/02/2014, 17:20

... These two parts of < /b> the < /b> protein < /b> remain associated by noncovalent interac- tion, probably involving sequences within the < /b> SEA domain. The < /b> contribution of < /b> five different amino acids at the < /b> proteolytic ... further investigate the < /b> role < /b> of < /b> the < /b> SEA domain in < /b> cleavage of < /b> membrane-tethered mucins we carried out s...

Ngày tải lên: 19/02/2014, 18:20

... Processing. Dept. of < /b> Computer Science TR-70, Rutgers University, New Brunswick, N.J. Reinhart, T;mya [1976] The < /b> Syntactic Domain of < /b> Anaphora. unpublished Ph.D. dissertation, Department of < /b> Foreign ... and LinBuistics, M.I.T. Rieger, Charles J. [1974] Conceptual Memory: A Theory and Compufer Program for Processing Ihe Meaning Content of < /b> Natural Language...

Ngày tải lên: 21/02/2014, 20:20

... assignment rules and then come back to the < /b> issue of < /b> whether this was a valid choice. Before the < /b> rules can be applied, each turn in < /b> the < /b> dialogue must be classi- fied into one of < /b> the < /b> following types based on ... effectiveness of < /b> Socratic tutoring in < /b> the < /b> BEE domain or Socratic tutoring in < /b> general. 3.2 Initiative Annotat...

Ngày tải lên: 22/02/2014, 02:20

... to stabilize their protein < /b> scaf- folds, allowing the < /b> proper positioning of < /b> the < /b> residues involved in < /b> PLP binding, substrate binding and modu- lation of < /b> the < /b> cofactor’s catalytic properties. The < /b> third cluster ... at the < /b> value determined from the < /b> amino acid sequence (45 320 Da). Measurement of < /b> the < /b> K d of < /b> P...

Ngày tải lên: 07/03/2014, 03:20