Báo cáo khoa học: " Retinoic acid inducible gene I Activates innate antiviral response against human parainfluenza virus type 3" pdf

... role in activation of innate antiviral response during HPIV3 infection. Moreover, RIGI was involved in activating both arms (NFκB/TNFα and IRF3/IFNα/β) of innate immunity following HPIV3 infection. In ... abrogates innate antiviral responseFigure 3 Inactivation of endogenous RIGI in A549 cells by dominant-negative RIGI (ΔRIGI) abrogates innate antiviral response. (a) RT-PCR a...

Ngày tải lên: 12/08/2014, 04:20

... Respir Cell Mol Biol 13, 547–554. 9 Giovine M, Pozzolini M, Fenoglio I, Scarfı ` S, Ghiazza M, Benatti U & Fubini B (2003) Crystalline silica incu- bated in ascorbic acid acquires a higher ... process named silicosis. Alveolar macrophages initiate the disease through their activation, which is the origin of the later dysfunctions. Ascorbic acid is known to selectively dissolve the qu...

Ngày tải lên: 23/03/2014, 10:20

... epithelial cells. Biomaterials 2009, 30:2790-2798. 18. Neri S, Mariani E, Meneghetti A, Cattini L, Facchini A: Calcein- Acetyoxymethyl Cytotoxicity Assay: Standardization of a Method Allowing Additional ... quantum efficiency was considered satisfactory for biological imaging. Luminescence life time decay measurement provided further evidence of the surface modification. Figure 2 displays the...

Ngày tải lên: 11/08/2014, 08:20

... DNA helicases, and their ATP-depend- ent DNA unwinding activities have been reviewed pre- viously [19]. In addition to its helicase activities, TFIIH is directly responsible for the recruitment ... essential tools in studies of NER. Results from a wide variety of biochemical and bio- physical studies have illuminated mechanistic aspects of DNA damage recognition and incision in eukaryotic cel...

Ngày tải lên: 07/03/2014, 12:20

... of HCVcc with lipoproteins might not be as optimal as in vivo passage of this virus in chimpanzees or in mice con- taining human liver xenografts. In fact, enhanced virus infectivity is observed ... Association of hepatitis C virus in human sera with beta-lipoprotein. Med Micro- biol Immunol 181, 293–300. 28 Thomssen R, Bonk S & Thiele A (1993) Density heter- ogeneities of hepat...

Ngày tải lên: 16/03/2014, 05:20

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Ngày tải lên: 07/08/2014, 15:20

... inhib- iting the viral replication in vitro. Antiviral activity of peptides and fusion phages in ovo Peptides were evaluated for their antiviral activity in ovo against AIV H9N2. Briefly, different ... 2: Inhibitory ability of the cyclic and linear peptides against the hemagglutination activity of the avian influenza virus H9N2. Inhibitory Molecule Minimum Inhibitory Concentration*...

Ngày tải lên: 12/08/2014, 04:21

... used in this study were chosen to minimize the risk of failure to identify SIRS, thereby minimizing the risk of the serious consequences to the patient that can arise when this diagnosis is missed ... With a high sensitivity of 97% there is a concurrent low specificity (64%), explaining the risk of false positive diagnoses of SIRS in our population of dogs. It is possible that a correlation b...

Ngày tải lên: 12/08/2014, 18:22

... NSP1 inhibits IFN-β promoter activation independent of IRF3 degradation Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I ... containing protein, RIG -I: retinoic acid inducible gene I, MAVS: mitochondrial antiviral- signaling protein, JAK: Janus Kinase, STAT: Signal Transducer and Activator of T...

Ngày tải lên: 18/06/2014, 18:20