Báo cáo khoa học: " Inhibition of Monkeypox virus replication by RNA interference" pdf

... SY: Inhibition of herpesvirus-6B RNA replication by short interference RNAs. J Biochem Mol Biol 2004, 37:383-385. 45. Shin D, Kim SI, Kim M, Park M: Efficient inhibition of hepatitis B virus replication ... processing of miRNA and shRNA by Dicer, assembly of resultant guide strand into the RNA- induced silencing complex (RISC), recognition of target viral RNA seq...

Ngày tải lên: 12/08/2014, 04:20

... after the existence of an acetylenzyme interme- diate was proposed. It was postulated by Krupka and Laidler that inhibition of AChE by substrate resulted from the inhibition of deacetylation [19]. ... completely block the exit of choline reinforcing the hypothesis of the existence of a backdoor Results obtained by the analyses of our data also suggest that there is onl...

Ngày tải lên: 16/03/2014, 16:20

... HSQC spectra of the reactions of a-Syn with quinone and DA. (A) Overlay of the 1 H- 15 N HSQC spectra of a-Syn (black) and the reaction product of a-Syn and Q (red). (B) Overlay of the 1 H- 15 N ... Molecular masses of the monomeric adducts as determined by electrospray mass spectrometry. Molecular masses were of the peaks detected by ESI-MS. Pattern shows incremental mole...

Ngày tải lên: 23/03/2014, 15:20

... the effect of GliPR suppression by siRNA on HIV-1 replication. Results: Induction of GliPR expression by HIV-1 was confi rmed in P4-CCR5 cells. When GliPR was suppressed by siRNA, HIV-1 replication ... HIV-1 pathology. Conclusions: The up-regulation of GliPR by HIV-1 and the early significant inhibition of HIV-1 replication mediated by knockdown of GliPR reveal Gli...

Ngày tải lên: 12/08/2014, 23:23

... for inhibition of HIV Inhibition of HIV-1 infectivity by non-cytotoxic concentra-tions of the P-TEFb inhibitors DRB, seliciclib and flavopiridolFigure 4 Inhibition of HIV-1 infectivity by non-cytotoxic ... concentrations of the P- TEFb inhibitors also decreased phosphorylation of the protein substrate. Phosphorylation of the largest subunit of DSIF by P-TEFb was i...

Ngày tải lên: 13/08/2014, 05:22

... most evident inhibition of virus replication was observed after 7 and 15 days using a-lactoferrin and a-lactalbumin, respectively. Native and esterified lactoferrin showed complete inhibition after ... as described by [25-27]. Abdelbacki et al. Virology Journal 2010, 7:26 http://www.virologyj.com/content/7/1/26 Page 2 of 6 RESEA R C H Open Access Inhibition of Tomato Yellow...

Ngày tải lên: 12/08/2014, 04:21

... Figure 5 shows the superimposed structures of DHPS and 5-methyltetrahydrofolate. The model of the methyltetrahydrofolate-binding site of MetS with one molecule of the substrate included was further ... cycle of cytochrome P450 [29]. Details of the potential binding and electron transfer events that may account for the uncompetitive inhibition of MetS by nitrobenzothiadiazole...

Ngày tải lên: 19/02/2014, 05:20

... effect of these compounds was different from that of choline (Fig. 6B). To check whether the toxic effects of atropine and ipratropium might be reversed by addition of excess amounts of choline, ... lysis) of the cell wall is an essential process for both cell viability and liberation of viru- lence factors. Inhibition of autolysis by excess cho- line might, in the first...

Ngày tải lên: 19/02/2014, 05:20

... altered by the presence of the inhibitor, and disrupting the electron transfer between the flavin and the second substrate mainly causes enzyme inhibition by Zn-ferrocyanide. Effect of Fld on the inhibition ... Trippi, V.S. (2000) Inhibition of wheat nitrate reductase a ctivity by zinc. B iol. Plant. 43 , 257–262. 21. Egash ira, T., Takayama, F . & Sakai, K. (2003) Inhib...

Ngày tải lên: 19/02/2014, 16:20

... inactivation of G APDH being metal- ion independent, whereas inhibition of GR and LDH by H 2 O 2 occurs most rapidly in the presence of metal ions. It is proposed that the inhibition of GAPDH and GR by these 1 O 2 -generated ... This inhibition was not stimulated by added Fe 2+ –EDTA. In contrast, rapid inhibition of GR by H 2 O 2 was only observed in the presence o...

Ngày tải lên: 21/02/2014, 03:20