Báo cáo khoa học: "Combined effects of hyperglycemic conditions and HIV-1 Nef: a potential model for induced HIV neuropathogenesis" docx

... Cassandra.Roschel@gmail.com; Muhammad Mukhtar - mukhtar.muhammad@gmail.com; Alagarsamy Srinivasan - alagarsamy.srinivasan@gmail.com; Mohammad Rafi - Mohammad.Rafi@jefferson.edu; Roger J Pomerantz - RPomeran@its.jnj.com; ... Philadelphia, PA 19107, USA and 6 Tibotec Inc. 1020 Stony Hill Road, Suite 300, Yardley, PA 19067, USA Email: Edward A Acheampong - eacheamp@yahoo.com; Cassandra R...

Ngày tải lên: 12/08/2014, 04:20

... luciferase values were normalized to protein concentration as assessed by a Bradford assay. Protein preparation and western blotting analysis Protein preparation and western blotting analysis ... Myc+Ras in the REF assay, this con- struct suppressed cotransformation activity at least as A B Fig. 4. Common and distinct transcriptional effects of Mxi1-SRa and Mxi1-SRb on downstr...

Ngày tải lên: 18/02/2014, 16:20

... Mca-Ala substrate Table 1. Kinetic parameters for the hydrolysis of the Mca-Ala substrate by rat, mouse and human somatic ACE. Kinetic parameters k cat and K m were obtained by inhibiting the activity ... Mca-Ala-Ser-Asp-Lys-DpaOH (Mca-Ala, 8 l M). Arrows show the inhibition of human and rat N-domain by RXP407 (A) or human and rat C-domain by RXPA380 (B). Inhibition profiles of...

Ngày tải lên: 16/03/2014, 13:20

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Ngày tải lên: 07/08/2014, 17:22

... for a three amino acid Met-Ala-Ser N-terminal extension to substitute for the lack of N-terminal acetylation. The sequence for the N-terminal 5¢ forward primer was 5¢-GGAATTCCATATGGCGAGC ATGGACGCCATCAAGAAGAAGATGC-3¢. ... 5¢-GGAATTCCATATGGCGAGC ATGGACGCCATCAAGAAGAAGATGC-3¢. As smTm uses the same C-terminal exon 9d as Tm 5a and Tm5b, the same 3¢ reverse primer was used. The ligated...

Ngày tải lên: 19/02/2014, 07:20

... cellular stress, as for example, oxidative damages caused by certain pharmaceuticals or lowered oxygen saturation of haemo- globin in various forms of hypoxia. In general, the target fluxes of a metabolic ... into ÔbasicÕ fluxes that are permanently required at an almost constant level to ensure stability and integrity of the cell, and ÔvariableÕ target fluxes that may vary accor...

Ngày tải lên: 07/03/2014, 15:20

... influenza: a protean pandemic threat. Proc Natl Acad Sci USA 2004, 101, 8156-8161. 12. Hatta M, Gao P, Halfmann P, Kawaoka Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. ... Experimental infection of the highly pathogenic H5N1 avian influenza virus 59 RA, Amonsin A, Payungporn S, Noppornpanth S, Wattanodorn S, Theambooniers A, Tantilertcharoen R...

Ngày tải lên: 07/08/2014, 23:22

... variable than the phenotypes of the ADR-design (Tab. III). 2.4. Statistical analysis The QTL analyses were performed for each trait separately across fam- ilies with the programs BIGMAP and ADRQLT ... coded as follows: short paternal allele ‘1’; long paternal allele ‘2’; and all deviating maternal alleles ‘3’. A unified coding of the EAC blood group marker was done with haplotype a...

Ngày tải lên: 14/08/2014, 13:22

... K12 and the side chains of N10 and Q64, which maintain the unusual Rama- chandran angles for the K12 residue, and a Ramachandran scatter plot for the K12 resi- dues in 21 TIM structures from various sources ... mutations Mousumi Banerjee 1 , Hemalatha Balaram 2 and Padmanabhan Balaram 1 1 Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India 2 Molecular Bi...

Ngày tải lên: 18/02/2014, 11:20

... 253–257. 34 Takeshima K, Chikushi A, Lee KK, Yonehara S & Matsuzaki K (2003) Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes. J Biol ... nonpeptides H4-(86–100) and HNr (Fig. 1) were tested for their bactericidal activity against Gram-negative and Gram- positive bacteria (Table 1). The bactericidal activities of HNr...

Ngày tải lên: 18/02/2014, 14:20